SCHEMBL16470372

SCHEMBL16470372

Clc1ccc(N2CSc3ccccc32)cc1

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.40
HPGD P15428 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
BRD4 O60885 6/20 0.39
BRD2 P25440 4/20 0.37
BRD3 Q15059 3/20 0.37
DRD4 P21917 2/20 0.36
TP53 P04637 1/20 0.36
MAPT P10636 1/20 0.36
BCHE P06276 2/20 0.36
ALB P02768 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11995114 0.85 SIGMAR1 (0.39) HPGDTP53MAPTMEN1KMT2A
SCHEMBL16470166 0.82 TSHR (0.43) LMNAHPGDTP53MAPTMEN1
SCHEMBL16470234 0.82 NPC1 (0.39) LMNAHPGDTP53MAPTBCHE
SCHEMBL28957204 0.79 NOTUM (0.33) MEN1KMT2A
SCHEMBL16469872 0.78 HTR1A (0.33) HPGDMEN1KMT2A
SCHEMBL16470117 0.78 BRD4 (0.39) BRD4TP53MAPTMEN1KMT2A
SCHEMBL27992893 0.78 KMT2A (0.37) LMNAHPGDL3MBTL1DRD4TP53
SCHEMBL16470622 0.76 HTR3A (0.40) HPGDBCHE
SCHEMBL31552864 0.76 HSD17B3 (0.34) LMNAHPGDL3MBTL1DRD4TP53
SCHEMBL16470286 0.70 PDCD1 (0.49) LMNAHPGDL3MBTL1MAPTBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9829605-B2 Polarized film, optical film, and image display device NITTO DENKO CORPORATION (JP) 2017-11-28 US disclosed
US-20160152002-A1 TRANSPARENT CONDUCTIVE LAMINATED FILM, METHOD FOR MANUFACTURING SAME, AND TOUCH PANEL NITTO DENKO CORPORATION (JP) 2016-06-02 US disclosed
US-20150152299-A1 ACTIVE ENERGY RAY CURABLE ADHESIVE COMPOSITION, POLARIZING FILM AND METHOD FOR PRODUCING SAME, OPTICAL FILM AND IMAGE DISPLAY DEVICE NITTO DENKO CORPORATION (JP) 2015-06-04 US disclosed
US-20150116817-A1 ACTIVE ENERGY RAY CURABLE ADHESIVE COMPOSITION, POLARIZING FILM AND METHOD FOR PRODUCING SAME, OPTICAL FILM AND IMAGE DISPLAY DEVICE NITTO DENKO CORPORATION (JP) 2015-04-30 US disclosed
US-20150049380-A1 POLARIZED FILM, OPTICAL FILM, AND IMAGE DISPLAY DEVICE NITTO DENKO CORPORATION (JP) 2015-02-19 US disclosed