SCHEMBL16470397

SCHEMBL16470397

C[SH](C)(=O)c1cccc(Cl)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.41
ALDH1A1 P00352 3/20 0.39
TSHR P16473 1/20 0.39
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
PARP1 P09874 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
HTT P42858 1/20 0.36
HTR3E A5X5Y0 2/20 0.36
HTR3B O95264 2/20 0.36
HTR3A P46098 2/20 0.36
HTR3D Q70Z44 2/20 0.36
HTR3C Q8WXA8 2/20 0.36
GAA P10253 1/20 0.36
PNMT P11086 2/20 0.35
CHRNA1 P02708 1/20 0.35
CHRNG P07510 1/20 0.35
ITGA5 P08648 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16469650 0.76 TSHR (0.42) MGLLALDH1A1TSHRMEN1KMT2A
SCHEMBL13758205 0.74 ACHE (0.50) MGLLALDH1A1TSHRMEN1KMT2A
SCHEMBL13591760 0.73 CYP3A4 (0.48) ALDH1A1TSHRMEN1KMT2ATDP1
SCHEMBL28291121 0.70 LMNA (0.44) ALDH1A1TSHRMEN1KMT2ALMNA
Tetramethylammonium Ion SCHEMBL11247535 0.69 TSHR (0.50) ALDH1A1TSHRPARP1TDP1PNMT
Chloromethane SCHEMBL27517684 0.68 TSHR (0.55) MGLLALDH1A1TSHRPARP1TDP1
SCHEMBL28140 0.68
SCHEMBL28129975 0.68 TSHR (0.61) MGLLALDH1A1TSHRMEN1KMT2A
Formaldehyde SCHEMBL10275626 0.66 ALDH1A1 (0.52) MGLLALDH1A1TSHRMEN1KMT2A
Methylamine SCHEMBL27796203 0.66 ALDH1A1 (0.60) ALDH1A1TSHRPARP1HTTHTR3E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109651202-B Method for synthesizing carbamate by using dimethyl sulfoxide ylide, amine and carbon dioxide 华南理工大学 2021-03-30 CN disclosed
WO-2020114150-A1 SYNTHESIS METHOD FOR SYNTHESIZING CARBAMATE USING DIMETHYL SULFOXIDE YLIDE, AMINE AND CARBON DIOXIDE 华南理工大学 2020-06-11 WO disclosed
US-9829605-B2 Polarized film, optical film, and image display device NITTO DENKO CORPORATION (JP) 2017-11-28 US disclosed
US-20160152002-A1 TRANSPARENT CONDUCTIVE LAMINATED FILM, METHOD FOR MANUFACTURING SAME, AND TOUCH PANEL NITTO DENKO CORPORATION (JP) 2016-06-02 US disclosed
US-20150152299-A1 ACTIVE ENERGY RAY CURABLE ADHESIVE COMPOSITION, POLARIZING FILM AND METHOD FOR PRODUCING SAME, OPTICAL FILM AND IMAGE DISPLAY DEVICE NITTO DENKO CORPORATION (JP) 2015-06-04 US disclosed
US-20150116817-A1 ACTIVE ENERGY RAY CURABLE ADHESIVE COMPOSITION, POLARIZING FILM AND METHOD FOR PRODUCING SAME, OPTICAL FILM AND IMAGE DISPLAY DEVICE NITTO DENKO CORPORATION (JP) 2015-04-30 US disclosed
US-20150049380-A1 POLARIZED FILM, OPTICAL FILM, AND IMAGE DISPLAY DEVICE NITTO DENKO CORPORATION (JP) 2015-02-19 US disclosed