Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.66 |
| ▸ | ACHE | P22303 | 5/20 | 0.61 |
| ▸ | BCHE | P06276 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | BACE1 | P56817 | 4/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PRKDC | P78527 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2502259 | 0.86 | MAPT (0.62) | PTGS2ACHEBCHEMAPTBACE1 | |
| SCHEMBL9686162 | 0.86 | PTGS2 (0.66) | PTGS2ACHEBCHEMAPTBACE1 | |
| SCHEMBL29559360 | 0.83 | PTGS2 (0.71) | PTGS2ACHEBCHEMAPTBACE1 | |
| SCHEMBL16504670 | 0.83 | PTGS2 (0.55) | PTGS2ACHEBCHEMAPTBACE1 | |
| SCHEMBL29406605 | 0.83 | PTGS2 (0.55) | PTGS2ACHEBCHEMAPTBACE1 | |
| SCHEMBL16504671 | 0.83 | PTGS2 (0.55) | PTGS2ACHEBCHEMAPTBACE1 | |
| SCHEMBL11791340 | 0.82 | ALDH3A1 (0.56) | PTGS2ACHEBCHEMAPTBACE1 | |
| SCHEMBL11795154 | 0.81 | PTGS2 (0.63) | PTGS2ACHEBCHEMAPTBACE1 | |
| SCHEMBL11795164 | 0.81 | PTGS2 (0.63) | PTGS2ACHEBCHEMAPTBACE1 | |
| SCHEMBL4313460 | 0.81 | ALDH1A1 (0.52) | PTGS2ACHEBCHEMAPTBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115850174-B | Fluorescent probe for detecting amine and preparation method and application thereof | 南京师范大学 | 2024-05-24 | — | — | CN | claimed |
| CN-115850174-A | Fluorescent probe for detecting amine and preparation method and application thereof | 南京师范大学 | 2023-03-28 | — | — | CN | claimed |
| CN-112225743-B | Quinolinyl near-infrared rhodamine fluorescent dye, ratiometric fluorescent probe, and synthesis and application thereof | 嘉兴学院 | 2021-10-08 | — | — | CN | claimed |
| CN-112225743-A | Quinolinyl near-infrared rhodamine fluorescent dye, ratiometric fluorescent probe, and synthesis and application thereof | 嘉兴学院 | 2021-01-15 | — | — | CN | claimed |
| US-7732534-B2 | Polymers functionalized with nitro compounds | BRIDGESTONE CORPORATION (JP) | 2010-06-08 | — | — | US | claimed |
| US-20080051519-A1 | Polymers functionalized with nitro compounds | BRIDGESTONE CORPORATION (JP) | 2008-02-28 | — | — | US | claimed |
| US-20080051552-A1 | Polymers functionalized with nitro compounds | BRIDGESTONE CORPORATION | 2008-02-28 | — | — | US | claimed |
| CN-115611894-B | Nitrogen-containing spiro compound or pharmaceutically acceptable salt thereof, and preparation method and application thereof | 心远(广州)药物研究有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-115850174-B | Fluorescent probe for detecting amine and preparation method and application thereof | 南京师范大学 | 2024-05-24 | — | — | CN | disclosed |
| CN-114432308-B | Application of nitrogenous spiro compound or pharmaceutically acceptable salt thereof in preparation of anti-influenza A virus drugs | 华南理工大学 | 2023-09-26 | — | — | CN | disclosed |
| CN-115850174-A | Fluorescent probe for detecting amine and preparation method and application thereof | 南京师范大学 | 2023-03-28 | — | — | CN | disclosed |
| CN-115611894-A | Nitrogen-containing spiro compound or pharmaceutically acceptable salt thereof, and preparation method and application thereof | 心远(广州)药物研究有限公司 | 2023-01-17 | — | — | CN | disclosed |
| CN-114432308-A | Application of nitrogen-containing spiro compound or pharmaceutically acceptable salt thereof in preparation of anti-influenza A virus medicine | 华南理工大学 | 2022-05-06 | — | — | CN | disclosed |
| US-4778893-A | FLUORESCENT; OXIDATION OF CHALCOGENS WITH HYDROGEN PEROXIDE | MILES INC. (US) | 1988-10-18 | — | — | US | disclosed |
| EP-0121743-B1 | OPTICAL INDICATOR CHALCOGEN COMPOUNDS AND USE | MILES LABORATORIES, INC. (US) | 1987-09-09 | — | — | EP | disclosed |
| US-4558130-A | FLUORESCENCE ON OXIDATION BY HYDROGEN PEROXIDE; PEROXIDASE DETERMINATION | MILES LABORATORIES, INC. (US) | 1985-12-10 | — | — | US | disclosed |
| EP-0156261-A2 | Fluorogenic dihydroquinolone and dihydrocoumarin indicators for hydrogen peroxide | MILES INC. (US) | 1985-10-02 | — | — | EP | disclosed |
| EP-0121743-A2 | Optical indicator chalcogen compounds and use | MILES LABORATORIES, INC. (US) | 1984-10-17 | — | — | EP | disclosed |
| US-4219651-A | FLUORESCENT DYES, OPTICAL BRIGHTENERS; CHEMICAL INTERMEDIATES | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-08-26 | — | — | US | disclosed |
| US-3971821-A | Production of aminobenzaldehydes | BASF AKTIENGESELLSCHAFT (DT) | 1976-07-27 | — | — | US | disclosed |