Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA7 | P43166 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | RECQL | P46063 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25835265 | 0.78 | CA1 (0.54) | CA1CA2CA7CA9MAOA | |
| SCHEMBL18971656 | 0.75 | CA1 (0.46) | CA1CA2CA7CA9MAOA | |
| SCHEMBL19887706 | 0.73 | CA1 (0.45) | CA1CA2CA7CA9MAOA | |
| SCHEMBL18971863 | 0.71 | CA1 (0.43) | CA1CA2CA7CA9MAOA | |
| SCHEMBL11242496 | 0.66 | TXNRD1 (0.41) | CA1CA2CA7CA9MAOA | |
| SCHEMBL19891984 | 0.65 | CA1 (0.53) | CA1CA2CA7CA9MAOA | |
| SCHEMBL5793477 | 0.64 | MAOA (0.56) | CA1CA2CA7CA9MAOA | |
| SCHEMBL13439628 | 0.64 | MAOA (0.56) | CA1CA2CA7CA9MAOA | |
| SCHEMBL15642543 | 0.63 | CA1 (1.00) | CA1CA2CA7CA9MAOA | |
| SCHEMBL30506306 | 0.63 | ALDH1A1 (0.62) | MAPTALDH1A1HPGDSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890106-B2 | Anti-cancer lead molecule | KING ABDULLAH UNIVERSITY OF SCIENCE & TECHNOLOGY (SA) | 2018-02-13 | — | — | US | disclosed |
| US-9890106-B2 | Anti-cancer lead molecule | KING ABDULLAH UNIVERSITY OF SCIENCE & TECHNOLOGY (SA) | 2018-02-13 | — | — | US | disclosed |
| WO-2016135633-A1 | CHOLESTERYL ESTER TRANSFER PROTEIN (CETP) INHIBITION IN THE TREATMENT OF CANCER | KING ABDULLAH UNIVERSITY OF SCIENCE & TECHNOLOGY (SA) | 2016-09-01 | — | — | WO | disclosed |
| US-20140107196-A1 | ANTI-CANCER LEAD MOLECULE | KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) | 2014-04-17 | — | — | US | disclosed |
| US-20140107196-A1 | ANTI-CANCER LEAD MOLECULE | KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) | 2014-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140107196-A1 | ANTI-CANCER LEAD MOLECULE | ACAT2, BRCA1, ALPG | CA1 4395/4885CA2 4843/4885CA7 4567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.