Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | RARG | P13631 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 3/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | EIF4A1 | P60842 | 2/20 | 0.34 |
| ▸ | ASAH1 | Q13510 | 3/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9914999 | 0.93 | RARB (0.39) | RARBRARARARGDHODHEIF4A1 | |
| SCHEMBL19512280 | 0.91 | RARB (0.46) | RARBRARARARGDHODHEIF4A1 | |
| SCHEMBL16474340 | 0.91 | RARB (0.34) | RARBRARARARGDHODHEIF4A1 | |
| SCHEMBL13005282 | 0.89 | RARB (0.35) | RARBRARARARGDHODHEIF4A1 | |
| SCHEMBL13005273 | 0.89 | SIRT2 (0.38) | RARBRARARARGKDM4E | |
| SCHEMBL13005275 | 0.88 | SIRT2 (0.39) | RARBASAH1KDM4E | |
| SCHEMBL13005285 | 0.85 | DGAT1 (0.33) | RARBKDM4E | |
| SCHEMBL16474339 | 0.85 | SIRT2 (0.37) | RARBKDM4E | |
| SCHEMBL18961305 | 0.82 | SIRT2 (0.36) | — | |
| SCHEMBL13005281 | 0.82 | S1PR1 (0.35) | RARBRARARARGASAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140197361-A1 | DICHROIC-PHOTOCHROMIC 2H-NAPHTHO[1,2-b]PYRAN COMPOUNDS AND DEVICES | ALPHAMICRON INCORPORATED (US) | 2014-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140197361-A1 | DICHROIC-PHOTOCHROMIC 2H-NAPHTHO[1,2-b]PYRAN COMPOUNDS AND DEVICES | NR0B2, NR0B1, DHCR24 | RARB 23/4885RARA 9/4885RARG 51/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.