Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18432742 | 0.92 | TAS1R3 (0.33) | NR3C1TSHRSMN1; SMN2 | |
| SCHEMBL40376 | 0.89 | TSHR (0.35) | NR3C1TSHRSMN1; SMN2 | |
| SCHEMBL24270802 | 0.77 | TSHR (0.33) | TSHRSMN1; SMN2 | |
| SCHEMBL19605886 | 0.77 | KDM4E (0.36) | — | |
| SCHEMBL18177040 | 0.76 | ELANE (0.38) | NR3C1 | |
| SCHEMBL22642564 | 0.76 | TSHR (0.32) | TSHRSMN1; SMN2 | |
| SCHEMBL12793115 | 0.75 | ELANE (0.41) | — | |
| SCHEMBL14747379 | 0.74 | RIPK1 (0.33) | NR3C1 | |
| SCHEMBL20047250 | 0.74 | RECQL (0.30) | — | |
| SCHEMBL19105207 | 0.74 | NR3C1 (0.35) | NR3C1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018067878-A1 | DEVICES AND METHODS FOR SAMPLE ANALYSIS | ABBOTT LABORATORIES (US) | 2018-04-12 | — | — | WO | disclosed |
| EP-2271346-B1 | MONOCYCLIC CGRP RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME (US) | 2014-01-01 | — | — | EP | disclosed |