SCHEMBL16475845

SCHEMBL16475845

c1ccc(-c2ccc3c(c2)c2cc(-c4ccc5c(c4)c4ccccc4n5-c4ccccc4)ccc2n3-c2nc(-c3ccccc3)c3ccccc3n2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.48
ALDH1A1 P00352 3/20 0.48
HPGD P15428 3/20 0.48
MAPT P10636 3/20 0.48
NPSR1 Q6W5P4 1/20 0.48
L3MBTL1 Q9Y468 4/20 0.46
ATM Q13315 3/20 0.45
LMNA P02545 1/20 0.45
MAPK1 P28482 2/20 0.41
POLB P06746 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
NUDT1 P36639 3/20 0.39
ADORA2A P29274 2/20 0.39
PTGER4 P35408 1/20 0.39
NPY5R Q15761 1/20 0.39
HTT P42858 1/20 0.38
KMT2A Q03164 4/20 0.38
MEN1 O00255 3/20 0.38
HSP90AA1 P07900 1/20 0.37
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15583014 1.00 KDM4E (0.48) KDM4EALDH1A1HPGDMAPTNPSR1
SCHEMBL22479831 1.00 KDM4E (0.48) KDM4EALDH1A1HPGDMAPTNPSR1
SCHEMBL16706367 1.00 KDM4E (0.48) KDM4EALDH1A1HPGDMAPTNPSR1
SCHEMBL16475838 1.00 KDM4E (0.48) KDM4EALDH1A1HPGDMAPTNPSR1
SCHEMBL15638499 1.00 KDM4E (0.48) KDM4EALDH1A1HPGDMAPTNPSR1
SCHEMBL15197764 1.00 KDM4E (0.48) KDM4EALDH1A1HPGDMAPTNPSR1
SCHEMBL16475779 1.00 KDM4E (0.48) KDM4EALDH1A1HPGDMAPTNPSR1
SCHEMBL29645234 0.99 KDM4E (0.49) KDM4EALDH1A1HPGDMAPTNPSR1
SCHEMBL10246658 0.99 KDM4E (0.49) KDM4EALDH1A1HPGDMAPTNPSR1
SCHEMBL16475809 0.98 KDM4E (0.46) KDM4EALDH1A1HPGDMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11917907-B2 Organic electroluminescent device ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2024-02-27 US disclosed
US-11917907-B2 Organic electroluminescent device ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2024-02-27 US disclosed
US-20230320207-A1 PLURALITY OF HOST MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-10-05 US disclosed
US-20230320207-A1 PLURALITY OF HOST MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-10-05 US disclosed
US-20230020540-A1 MULTI-COMPONENT HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-01-19 US disclosed
US-20220216430-A1 MULTI-COMPONENT HOST MATERIAL AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2022-07-07 US disclosed
US-20220216429-A1 MULTI-COMPONENT HOST MATERIAL AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2022-07-07 US disclosed
US-20220102633-A1 ORGANIC ELECTROLUMINESCENT DEVICE DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2022-03-31 US disclosed
US-11130747-B2 Plurality of host materials and an organic electroluminescence device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD (KR) 2021-09-28 US disclosed
US-20210210697-A1 MULTI-COMPONENT HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-07-08 US disclosed
US-20170047527-A1 MULTI-COMPONENT HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2017-02-16 US disclosed
US-9287512-B2 Organic electroluminescent compounds, layers and organic electroluminescent device using the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2016-03-15 US disclosed
US-20150357583-A1 Novel Organic Electroluminescent Compounds, Layers and Organic Electroluminescent Device Using The Same DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2015-12-10 US disclosed
US-20150357583-A1 Novel Organic Electroluminescent Compounds, Layers and Organic Electroluminescent Device Using The Same DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2015-12-10 US disclosed
US-20150171346-A1 Novel Organic Electroluminescent Compounds and Organic Electroluminescent Device Using The Same ROHM & HAAS ELECT MAT (KR) 2015-06-18 US disclosed
US-20150171346-A1 Novel Organic Electroluminescent Compounds and Organic Electroluminescent Device Using The Same ROHM & HAAS ELECT MAT (KR) 2015-06-18 US disclosed
US-20150159084-A1 NOVEL COMBINATION OF A HOST COMPOUND AND A DOPANT COMPOUND AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MAT (KR) 2015-06-11 US disclosed
US-20150159084-A1 NOVEL COMBINATION OF A HOST COMPOUND AND A DOPANT COMPOUND AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MAT (KR) 2015-06-11 US disclosed
US-20140107338-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME Rohm, and Haas Electronic Materials Korea Ltd. (KR) 2014-04-17 US disclosed
US-20140107338-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME Rohm, and Haas Electronic Materials Korea Ltd. (KR) 2014-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11130747-B2 Plurality of host materials and an organic electroluminescence device comprising the same SOD1, TERT, TELO2 KDM4E 2736/4885ALDH1A1 1275/4885HPGD 4292/4885
US-20220102633-A1 ORGANIC ELECTROLUMINESCENT DEVICE SOD1, TRPC6, L1CAM KDM4E 2489/4885ALDH1A1 1929/4885HPGD 3448/4885
US-20150171346-A1 Novel Organic Electroluminescent Compounds and Organic Electroluminescent Device Using The Same OR10J3, VDAC2, KCNN2 KDM4E 826/4885ALDH1A1 590/4885HPGD 2828/4885
US-20140107338-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME OR10J3, VDAC2, KCNN2 KDM4E 826/4885ALDH1A1 590/4885HPGD 2828/4885
US-20220216429-A1 MULTI-COMPONENT HOST MATERIAL AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME LIMS1, ORC3, MCM4 KDM4E 2097/4885ALDH1A1 3153/4885HPGD 3792/4885
US-20230320207-A1 PLURALITY OF HOST MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OR10J3, EPCAM, NECTIN4 KDM4E 1968/4885ALDH1A1 1322/4885HPGD 4665/4885
US-20220216430-A1 MULTI-COMPONENT HOST MATERIAL AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME LIMS1, ORC3, MCM4 KDM4E 2097/4885ALDH1A1 3153/4885HPGD 3792/4885
US-11917907-B2 Organic electroluminescent device SOD1, TRPC6, L1CAM KDM4E 2489/4885ALDH1A1 1929/4885HPGD 3448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.