Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 7/20 | 0.48 |
| ▸ | NOS1 | P29475 | 6/20 | 0.48 |
| ▸ | NOS3 | P29474 | 5/20 | 0.48 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2231028 | 0.84 | NOS2 (0.55) | NOS2NOS1NOS3 | |
| SCHEMBL9313998 | 0.74 | NOS2 (0.54) | NOS2NOS1NOS3 | |
| SCHEMBL16228218 | 0.74 | NOS2 (0.58) | NOS2NOS1NOS3 | |
| SCHEMBL9254075 | 0.73 | NOS2 (0.53) | NOS2NOS1NOS3 | |
| SCHEMBL10144472 | 0.72 | NOS2 (0.52) | NOS2NOS1NOS3 | |
| SCHEMBL13040577 | 0.72 | NOS2 (0.68) | NOS2NOS1NOS3 | |
| SCHEMBL1126483 | 0.71 | NOS1 (0.42) | NOS2NOS1NOS3 | |
| SCHEMBL11829782 | 0.69 | NOS2 (0.64) | NOS2NOS1NOS3 | |
| SCHEMBL15470594 | 0.68 | NOS2 (0.46) | NOS2NOS1NOS3 | |
| SCHEMBL7051201 | 0.68 | NOS2 (0.94) | NOS2NOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303329-A1 | ANTIFUNGAL COMBINATION THERAPY | F2G Limited (GB) | 2011-04-06 | — | — | EP | disclosed |
| WO-2009144473-A1 | ANTIFUNGAL COMBINATION THERAPY | F2G LIMITED (GB) | 2009-12-03 | — | — | WO | disclosed |