Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 9/20 | 0.94 |
| ▸ | NOS1 | P29475 | 9/20 | 0.94 |
| ▸ | NOS3 | P29474 | 7/20 | 0.94 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7051534 | 0.97 | NOS2 (1.00) | NOS2NOS1NOS3 | |
| SCHEMBL7049127 | 0.90 | NOS1 (0.82) | NOS2NOS1NOS3 | |
| SCHEMBL17721458 | 0.84 | NOS2 (0.79) | NOS2NOS1NOS3 | |
| SCHEMBL19405126 | 0.81 | NOS2 (0.69) | NOS2NOS1NOS3 | |
| SCHEMBL7730401 | 0.81 | NOS1 (0.77) | NOS2NOS1NOS3 | |
| SCHEMBL7736686 | 0.80 | NOS1 (1.00) | NOS2NOS1NOS3 | |
| SCHEMBL8330656 | 0.80 | NOS2 (0.77) | NOS2NOS1NOS3 | |
| Hydrochloric Acid SCHEMBL8192143 | 0.78 | NOS2 (0.75) | NOS2NOS1NOS3 | |
| SCHEMBL7049247 | 0.78 | NOS2 (0.77) | NOS2NOS1NOS3 | |
| SCHEMBL26538156 | 0.78 | NOS2 (1.00) | NOS2NOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003013523-A1 | SH3 PROTEIN DOMAINS AND THEIR LIGANDS | ADELAIDE RESEARCH & INNOVATION PTY LTD (AU) | 2003-02-20 | — | — | WO | claimed |
| US-5972975-A | Substituted 2-aminopyridines as inhibitors of nitric oxide synthase | MERCK & CO., INC. (US) | 1999-10-26 | — | — | US | claimed |
| WO-1996018616-A1 | SUBSTITUTED 2-AMINOPYRIDINES AS INHIBITORS OF NITRIC OXIDE SYNTHASE | MERCK & CO., INC. (US) | 1996-06-20 | — | — | WO | claimed |
| WO-2003013523-A1 | SH3 PROTEIN DOMAINS AND THEIR LIGANDS | ADELAIDE RESEARCH & INNOVATION PTY LTD (AU) | 2003-02-20 | — | — | WO | disclosed |
| US-5972975-A | Substituted 2-aminopyridines as inhibitors of nitric oxide synthase | MERCK & CO., INC. (US) | 1999-10-26 | — | — | US | disclosed |
| WO-1996018616-A1 | SUBSTITUTED 2-AMINOPYRIDINES AS INHIBITORS OF NITRIC OXIDE SYNTHASE | MERCK & CO., INC. (US) | 1996-06-20 | — | — | WO | disclosed |