Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | TTR | P02766 | 2/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16477279 | 0.91 | MAPT (0.50) | MAPTCSNK2A2CSNK2BCSNK2A1TP53 | |
| SCHEMBL16477282 | 0.86 | TTR (0.63) | MAPTTTRKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL1611070 | 0.80 | ALPG (0.59) | MAPTCSNK2A2CSNK2BCSNK2A1TP53 | |
| SCHEMBL16477278 | 0.78 | MAPT (0.60) | MAPTCSNK2A2CSNK2BCSNK2A1TP53 | |
| SCHEMBL26936175 | 0.75 | MAPT (0.51) | MAPTCSNK2A2CSNK2BCSNK2A1TP53 | |
| SCHEMBL19217398 | 0.75 | CSNK2A2 (0.62) | MAPTCSNK2A2CSNK2BCSNK2A1TP53 | |
| SCHEMBL21467879 | 0.74 | TTR (0.58) | MAPTCSNK2A2CSNK2BCSNK2A1TP53 | |
| SCHEMBL9980172 | 0.74 | ALPG (0.53) | MAPTCSNK2A2CSNK2BCSNK2A1TP53 | |
| SCHEMBL5456535 | 0.73 | ALDH1A1 (0.51) | MAPTCSNK2A2CSNK2BCSNK2A1TP53 | |
| SCHEMBL352535 | 0.73 | MAOA (0.67) | MAPTTP53TTRALPGHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9163002-B2 | Methodology for the synthesis of xanthones | UNIVERSITY OF SOUTH CAROLINA (US) | 2015-10-20 | — | — | US | disclosed |
| US-20140107354-A1 | New Methodology for the Synthesis of Xanthones | UNIVERSITY OF SOUTH CAROLINA | 2014-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140107354-A1 | New Methodology for the Synthesis of Xanthones | XDH, TYR, NISCH | MAPT 2203/4885CSNK2A2 1218/4885CSNK2B 1473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.