Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PRKDC | P78527 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12611490 | 0.85 | ALDH1A1 (0.58) | ALDH1A1LMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL67818 | 0.81 | ALDH1A1 (0.64) | ALDH1A1LMNASMN1; SMN2PRKDCKDM4E | |
| SCHEMBL30636721 | 0.81 | ALDH1A1 (0.64) | ALDH1A1LMNASMN1; SMN2PRKDCKDM4E | |
| SCHEMBL15842615 | 0.81 | AHR (0.55) | ALDH1A1LMNAPRKDCPOLBTSHR | |
| SCHEMBL11828153 | 0.79 | NQO1 (0.58) | ALDH1A1LMNASMN1; SMN2PRKDCMAPT | |
| SCHEMBL5449826 | 0.78 | GABRP (0.47) | ALDH1A1LMNAMAPTKMT2AKDM4E | |
| SCHEMBL31290722 | 0.78 | PIM1 (0.64) | ALDH1A1LMNASMN1; SMN2PRKDCMAPT | |
| SCHEMBL2490464 | 0.78 | PIM1 (0.64) | ALDH1A1LMNASMN1; SMN2PRKDCMAPT | |
| SCHEMBL10793717 | 0.78 | KDM4E (0.53) | ALDH1A1LMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL31506370 | 0.78 | ALDH1A1 (0.51) | ALDH1A1LMNASMN1; SMN2PRKDCMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118791455-A | Synthetic method for preparing 3, 4-dichloro coumarin from 4-chloro coumarin | 广西大学 | 2024-10-18 | — | — | CN | disclosed |
| US-20070060595-A1 | Novel fused heterocyclic compound and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-03-15 | — | — | US | disclosed |
| EP-1671962-A1 | NOVEL FUSED HETEROCYCLIC COMPOUND AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-06-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060595-A1 | Novel fused heterocyclic compound and use thereof | JUN, CHUK, RELA | ALDH1A1 677/4885LMNA 4382/4885SMN1; SMN2 4532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.