SCHEMBL1647741

SCHEMBL1647741

CN[C@@H]([C]=O)CCC(N)=O

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.39
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39
KMT2A Q03164 1/20 0.39
DPP4 P27487 1/20 0.36
DPP8 Q6V1X1 1/20 0.36
DPP9 Q86TI2 1/20 0.36
BMP1 P13497 1/20 0.35
ANPEP P15144 1/20 0.31
ENPEP Q07075 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3392906 1.00 ALOX15 (0.39) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL1970042 0.81 ANPEP (0.48) BMP1ANPEPENPEP
SCHEMBL7213193 0.81 ALOX15 (0.40) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL7352206 0.80 DPP4 (0.38) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL11363514 0.80 DPP4 (0.38) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL3075720 0.78
SCHEMBL6039517 0.78
SCHEMBL9545378 0.78
SCHEMBL21724570 0.76 CTSD (0.39) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL2246163 0.75 CTSC (0.37) ALOX15BLMPMP22KMT2ADPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080097078-A1 Antibacterial activity against vancomycin-resistant bacteria SHIONOGI & CO., LTD. (JP) 2008-04-24 US claimed
EP-1818340-A1 GLYCOPEPTIDE ANTIBIOTIC MONOMER DERIVATIVES National University Corporation Nagoya University (JP) 2007-08-15 EP claimed
US-8778874-B2 Glycopeptide antibiotic monomer derivatives NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2014-07-15 US disclosed
US-8481696-B2 Glycosylated glycopeptide antibiotic derivatives SHIONOGI & CO., LTD. (JP) 2013-07-09 US disclosed
EP-2314599-A1 Glycopeptide antibiotic monomer derivatives National University Corporation Nagoya University (JP) 2011-04-27 EP disclosed
US-20100286364-A1 GLYCOSYLATED GLYCOPEPTIDE ANTIBIOTIC DERIVATIVES SHIONOGI & CO., LTD. (JP) 2010-11-11 US disclosed
EP-2233495-A1 GLYCOSYLATED GLYCOPEPTIDE ANTIBIOTIC DERIVATIVE Shionogi & Co., Ltd. (JP) 2010-09-29 EP disclosed
US-20080097078-A1 Antibacterial activity against vancomycin-resistant bacteria SHIONOGI & CO., LTD. (JP) 2008-04-24 US disclosed
EP-1818340-A1 GLYCOPEPTIDE ANTIBIOTIC MONOMER DERIVATIVES National University Corporation Nagoya University (JP) 2007-08-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286364-A1 GLYCOSYLATED GLYCOPEPTIDE ANTIBIOTIC DERIVATIVES CSGALNACT1, OGT, GALNT1 ALOX15 3576/4885BLM 4103/4885PMP22 4474/4885
US-20080097078-A1 Antibacterial activity against vancomycin-resistant bacteria CSGALNACT1, MON2, NR2C2 ALOX15 4615/4885BLM 4169/4885PMP22 4221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.