SCHEMBL3392906

SCHEMBL3392906

CN[C@H]([C]=O)CCC(N)=O

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.39
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39
KMT2A Q03164 1/20 0.39
DPP4 P27487 1/20 0.36
DPP8 Q6V1X1 1/20 0.36
DPP9 Q86TI2 1/20 0.36
BMP1 P13497 1/20 0.35
ANPEP P15144 1/20 0.31
ENPEP Q07075 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1647741 1.00 ALOX15 (0.39) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL1970042 0.81 ANPEP (0.48) BMP1ANPEPENPEP
SCHEMBL7213193 0.81 ALOX15 (0.40) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL7352206 0.80 DPP4 (0.38) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL11363514 0.80 DPP4 (0.38) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL3075720 0.78
SCHEMBL6039517 0.78
SCHEMBL9545378 0.78
SCHEMBL21724570 0.76 CTSD (0.39) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL2246163 0.75 CTSC (0.37) ALOX15BLMPMP22KMT2ADPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1451209-A4 TETRA-,PENTA-,HEXA- AND HEPTAPEPTIDES HAVING ANTIANGIOGENIC ACTIVITY ABBOTT LAB (US) 2009-06-03 EP claimed
US-20080071062-A1 TETRA-, PENTA-, HEXA- AND HEPTAPEPTIDES HAVING ANTIANGIOGENIC ACTIVITY HAVIV FORTUNA 2008-03-20 US claimed
EP-1461356-A4 HEXA-, HEPTA-, AND OCTAPEPTIDES HAVING ANTIANGIOGENIC ACTIVITY ABBOTT LAB (US) 2007-12-12 EP claimed
US-20070167376-A1 Hexa-, Hepta-, and Octapeptides Having Antiangiogenic Activity HAVIV FORTUNA 2007-07-19 US claimed
US-7169888-B2 Tetra-, penta-, hexa- and heptapeptides having antiangiogenic activity ABBOTT LABORATORIES (US) 2007-01-30 US claimed
US-7122625-B2 Hexa-, hepta-, and octapeptides having antiangiogenic activity ABBOTT LABORATORIES (US) 2006-10-17 US claimed
US-20060194737-A1 Hepta-, octa-and nonapeptides having antiangiogenic activity HAVIV FORTUNA 2006-08-31 US claimed
US-7067490-B2 Hepta-, Octa-and nonapeptides having antiangiogenic activity ABBOTT LABORATORIES (US) 2006-06-27 US claimed
EP-1461356-A2 HEXA-, HEPTA-, AND OCTAPEPTIDES HAVING ANTIANGIOGENIC ACTIVITY Abbott Laboratories (US) 2004-09-29 EP claimed
EP-1451210-A2 HEPTA-, OCTA- AND NONAPEPTIDES HAVING ANTIANGIOGENIC ACTIVITY Abbott Laboratories (US) 2004-09-01 EP claimed
US-20030125261-A1 Penta- and hexapeptides having antiangiogenic activity ABBOTT LABORATORIES 2003-07-03 US claimed
US-20030119745-A1 HEXA- and heptapeptides having antiangiogenic activity ABBOTT LABORATORIES 2003-06-26 US claimed
US-20030119746-A1 Hepta-and octapeptides having antiangiogenic activity ABBOTT LABORATORIES 2003-06-26 US claimed
US-20030114386-A1 Hexa-, hepta-, and octapeptides having antiangiogenic activity ABBVIE INC. 2003-06-19 US claimed
US-20030109455-A1 HEPTA-, OCTA-and nonapeptides having antiangiogenic activity ABBVIE INC. 2003-06-12 US claimed
US-20030105023-A1 Tetra-, penta-, hexa- and heptapeptides having antiangiogenic activity ABBVIE INC. 2003-06-05 US claimed
US-20030105022-A1 Tetra-, penta-, hexa- and heptapeptides having antiangiogenic activity ABBOTT LABORATORIES 2003-06-05 US claimed
US-20030096758-A1 HEPTA-, OCTA- and nonapeptides having antiangiogenic activity ABBOTT LABORATORIES 2003-05-22 US claimed
WO-2003037268-A2 HEPTA-, OCTA- AND NONAPEPTIDES HAVING ANTIANGIOGENIC ACTIVITY ABBOTT LABORATORIES (US) 2003-05-08 WO claimed
WO-2003037266-A2 TETRA-, PENTA-, HEXA- AND HEPTAPEPTIDES HAVING ANTIANGIOGENIC ACTIVITY ABBOTT LABORATORIES (US) 2003-05-08 WO claimed