Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | BMP1 | P13497 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1647741 | 0.81 | ALOX15 (0.39) | ALOX15BLMPMP22KMT2ADPP4 | |
| SCHEMBL3392906 | 0.81 | ALOX15 (0.39) | ALOX15BLMPMP22KMT2ADPP4 | |
| SCHEMBL7352206 | 0.78 | DPP4 (0.38) | ALOX15BLMPMP22KMT2ADPP4 | |
| SCHEMBL11363514 | 0.78 | DPP4 (0.38) | ALOX15BLMPMP22KMT2ADPP4 | |
| SCHEMBL2246172 | 0.76 | CTSC (0.37) | ALOX15BLMPMP22KMT2ADPP4 | |
| SCHEMBL2246163 | 0.76 | CTSC (0.37) | ALOX15BLMPMP22KMT2ADPP4 | |
| SCHEMBL77561 | 0.75 | DPP8 (0.54) | ALOX15BLMPMP22KMT2ADPP4 | |
| SCHEMBL77560 | 0.75 | DPP8 (0.54) | ALOX15BLMPMP22KMT2ADPP4 | |
| SCHEMBL21724570 | 0.74 | CTSD (0.39) | ALOX15BLMPMP22KMT2ADPP4 | |
| SCHEMBL10728037 | 0.71 | DPP4 (0.43) | ALOX15BLMPMP22KMT2ADPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613738-B1 | Comprising 1,2-dihydroxy-homotyrosine, 4-hydroxyproline, threonine, glutamine, 3-,4-dihydroxymethylproline, 4,5-dihydroxyornithine and lipid | HMV CORPORATION | 2003-09-02 | — | — | US | disclosed |
| WO-2000009735-A1 | A CYCLIC LIPOPEPTIDE FROM CRYPTOSPORIOPSIS QUERCINA POSSESSING ANTIFUNGAL ACTIVITY | STROBEL GARY A (US) | 2000-02-24 | — | — | WO | disclosed |