Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.77 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.60 |
| ▸ | CA9 | Q16790 | 4/20 | 0.60 |
| ▸ | CA1 | P00915 | 3/20 | 0.60 |
| ▸ | CA2 | P00918 | 3/20 | 0.60 |
| ▸ | CA7 | P43166 | 3/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL118026 | 0.88 | KDR (1.00) | KDRPDK1TRPV1CA9CA1 | |
| SCHEMBL29364392 | 0.88 | KDR (1.00) | KDRPDK1TRPV1CA9CA1 | |
| SCHEMBL13945722 | 0.86 | KDR (0.78) | KDRPDK1TRPV1CA9CA1 | |
| SCHEMBL11087744 | 0.85 | KDR (0.68) | KDRPDK1TRPV1CA9CA1 | |
| SCHEMBL12413876 | 0.85 | KDR (0.82) | KDRPDK1TRPV1CA9CA1 | |
| SCHEMBL16884951 | 0.84 | AR (0.57) | KDRHTTCA9AR | |
| SCHEMBL4548158 | 0.83 | KDR (0.90) | KDRHTTPDK1TRPV1CA9 | |
| SCHEMBL3644352 | 0.83 | KDR (0.84) | KDRHTTPDK1TRPV1CA9 | |
| SCHEMBL12387674 | 0.83 | KDR (0.78) | KDRHTTPDK1TRPV1CA9 | |
| SCHEMBL13004799 | 0.82 | KDR (0.82) | KDRHTTPDK1TRPV1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10793527-B2 | Adenosine monophosphate-activated protein kinase agonist | NATIONAL YANG-MING UNIVERSITY (TW) | 2020-10-06 | — | — | US | disclosed |
| US-20190194142-A1 | AN ADENOSINE MONOPHOSPHATE-ACTIVATED PROTEIN KINASE AGONIST | NATIONAL YANG-MING UNIVERSITY (TW) | 2019-06-27 | — | — | US | disclosed |
| US-9216950-B2 | Agonists of Src homology-2 containing protein tyrosine phosphatase-1 and treatment methods using the same | NATIONAL TAIWAN UNIVERSITY (TW) | 2015-12-22 | — | — | US | disclosed |
| US-9090617-B1 | Agonists of Src homology-2 containing protein tyrosine phosphatase-1 and treatment methods using the same | NATIONAL TAIWAN UNIVERSITY (TW) | 2015-07-28 | — | — | US | disclosed |
| US-20150191467-A1 | AGONISTS OF SRC HOMOLOGY-2 CONTAINING PROTEIN TYROSINE PHOSPHATASE-1 AND TREATMENT METHODS USING THE SAME | RAND BIOSCIENCES (KR) | 2015-07-09 | — | — | US | disclosed |
| US-20140200239-A1 | AGONISTS OF SRC HOMOLOGY-2 CONTAINING PROTEIN TYROSINE PHOSPHATASE-1 AND TREATMENT METHODS USING THE SAME | NATIONAL TAIWAN UNIVERSITY (TW) | 2014-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150191467-A1 | AGONISTS OF SRC HOMOLOGY-2 CONTAINING PROTEIN TYROSINE PHOSPHATASE-1 AND TREATMENT METHODS USING THE SAME | SRC, PTPRCAP, GRB2 | KDR 1107/4885HTT 3607/4885PDK1 2591/4885 |
| US-20190194142-A1 | AN ADENOSINE MONOPHOSPHATE-ACTIVATED PROTEIN KINASE AGONIST | PRKAG1, PRKAG2, PRKAB1 | KDR 1064/4885HTT 4814/4885PDK1 90/4885 |
| US-10793527-B2 | Adenosine monophosphate-activated protein kinase agonist | PRKAG1, PRKAG2, PRKAB1 | KDR 851/4885HTT 4831/4885PDK1 100/4885 |
| US-20140200239-A1 | AGONISTS OF SRC HOMOLOGY-2 CONTAINING PROTEIN TYROSINE PHOSPHATASE-1 AND TREATMENT METHODS USING THE SAME | SRC, PTPRCAP, GRB2 | KDR 1107/4885HTT 3607/4885PDK1 2591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.