Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16480419 | 0.67 | MAPT (0.52) | ALDH1A1GAAKMT2AHPGDMAPT | |
| SCHEMBL6207077 | 0.61 | KMT2A (0.33) | SMN1; SMN2ALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL6236056 | 0.61 | CHRM4 (0.49) | SMN1; SMN2ALDH1A1ACHEMAPTRAB9A | |
| SCHEMBL1432868 | 0.60 | MAPT (0.38) | SMN1; SMN2ALDH1A1GAAKMT2ABCHE | |
| SCHEMBL10181202 | 0.60 | — | — | |
| SCHEMBL12324408 | 0.58 | JAK3 (0.36) | SMN1; SMN2ALDH1A1GAAKMT2ABCHE | |
| SCHEMBL28403533 | 0.58 | HRH3 (0.53) | SMN1; SMN2ALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL7075696 | 0.58 | MAOA (0.60) | SMN1; SMN2ALDH1A1KMT2ABCHEACHE | |
| SCHEMBL14940606 | 0.58 | MAPT (0.39) | SMN1; SMN2ALDH1A1KMT2ABCHEACHE | |
| SCHEMBL28813970 | 0.58 | MAOA (0.45) | SMN1; SMN2ALDH1A1BCHEACHEHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068592-A1 | INHIBITORS OF CYSTATHIONINE BETA SYNTHASE TO REDUCE THE NEUROTOXIC OVERPRODUCTION OF ENDOGENOUS HYDROGEN SULFIDE | FONDATION JEROME LEJEUNE (FR) | 2013-05-16 | — | — | WO | disclosed |