Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HASPIN | Q8TF76 | 7/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 2/20 | 0.39 |
| ▸ | PIM1 | P11309 | 3/20 | 0.38 |
| ▸ | TDO2 | P48775 | 2/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 2/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16483348 | 1.00 | HASPIN (0.41) | HASPINPIK3CDPIK3CBPIK3CGTNF | |
| SCHEMBL16483126 | 0.90 | PIK3CD (0.41) | HASPINPIK3CDPIK3CBPIK3CGTNF | |
| SCHEMBL16483148 | 0.90 | PIK3CD (0.41) | HASPINPIK3CDPIK3CBPIK3CGTNF | |
| SCHEMBL16483566 | 0.90 | HASPIN (0.40) | HASPINPIK3CDPIK3CBPIK3CGTNF | |
| SCHEMBL16483354 | 0.90 | TNF (0.39) | HASPINPIK3CDPIK3CBPIK3CGTNF | |
| SCHEMBL16483153 | 0.90 | HASPIN (0.44) | HASPINPIK3CDPIK3CBPIK3CGTNF | |
| SCHEMBL17341226 | 0.89 | L3MBTL1 (0.40) | KDM4EATML3MBTL1 | |
| SCHEMBL16483356 | 0.85 | DYRK1A (0.39) | TNFKDM4EATML3MBTL1 | |
| SCHEMBL16483315 | 0.85 | MAOA (0.42) | TNFTOP2AKDM4EATML3MBTL1 | |
| SCHEMBL17341426 | 0.85 | ALDH1A1 (0.42) | KDM4EATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |