SCHEMBL16484387

SCHEMBL16484387

c1ccc2c(c1)oc1c(-c3ccc(-n4c5ccccc5c5c6sc7c(ccc8c7c7ccccc7n8-c7ccc(-c8cccc9c8oc8ccccc89)cc7)c6ccc54)cc3)cccc12

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.43
PRKDC P78527 5/20 0.37
GGPS1 O95749 1/20 0.33
PIK3CD O00329 1/20 0.32
PIK3CB P42338 1/20 0.32
PTGES2 Q9H7Z7 1/20 0.31
ATM Q13315 2/20 0.31
KDM4E B2RXH2 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16283074 0.96 ALOX5 (0.40) ALOX5PRKDCGGPS1PTGES2ATM
SCHEMBL15759589 0.94 ALOX5 (0.40) ALOX5PRKDCGGPS1PIK3CDPIK3CB
SCHEMBL15804131 0.93 ALOX5 (0.39) ALOX5PRKDCGGPS1PIK3CDPIK3CB
SCHEMBL15804116 0.90 ALOX5 (0.47) ALOX5PRKDCGGPS1PIK3CDPIK3CB
SCHEMBL16482224 0.89 ALOX5 (0.39) ALOX5PRKDCGGPS1PIK3CDPIK3CB
SCHEMBL10108537 0.89 ALOX5 (0.36) ALOX5PRKDCATMKDM4EL3MBTL1
SCHEMBL16484399 0.89 ALOX5 (0.46) ALOX5PRKDCGGPS1PIK3CDPIK3CB
SCHEMBL16484406 0.89 ALOX5 (0.44) ALOX5PRKDCGGPS1PIK3CDPIK3CB
SCHEMBL16282998 0.89 ALOX5 (0.36) ALOX5PRKDCGGPS1ATMKDM4E
SCHEMBL17433201 0.89 ALOX5 (0.39) ALOX5PRKDCGGPS1PIK3CDPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190194219-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS EQUIPPED WITH SAME IDEMITSU KOSAN CO., LTD. (JP) 2019-06-27 US disclosed
US-9960364-B2 Ladder compound, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-05-01 US disclosed
US-9960364-B2 Ladder compound, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-05-01 US disclosed
US-20150270496-A1 LADDER COMPOUND, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMIITSU KOSAN CO., LTD. (JP) 2015-09-24 US disclosed
US-20150270496-A1 LADDER COMPOUND, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMIITSU KOSAN CO., LTD. (JP) 2015-09-24 US disclosed
WO-2014057684-A1 LADDER COMPOUND, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME 出光興産株式会社 (JP) 2014-04-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150270496-A1 LADDER COMPOUND, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME YBX1, ATXN2L, ATXN2 ALOX5 1455/4885PRKDC 4771/4885GGPS1 4134/4885
US-20190194219-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS EQUIPPED WITH SAME OR10J3, EML4, AOC2 ALOX5 3311/4885PRKDC 2743/4885GGPS1 1702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.