SCHEMBL16484641

SCHEMBL16484641

N#Cc1ccc(-c2cc(-c3ccc(C#N)cc3)cc(N(c3ccccc3)c3cccc(-c4ccc5c6c(cccc46)-c4c-5c(-c5ccccc5)c5ccccc5c4-c4ccccc4)c3)c2)cc1

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 1/20 0.33
ALDH1A1 P00352 2/20 0.32
ATM Q13315 1/20 0.32
GABRA1 P14867 1/20 0.32
GABRG2 P18507 1/20 0.32
GABRB3 P28472 1/20 0.32
GABRA5 P31644 1/20 0.32
GABRA3 P34903 1/20 0.32
KAT6A Q92794 1/20 0.32
PDK2 Q15119 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CSF1R P07333 1/20 0.31
FASN P49327 1/20 0.31
MYC P01106 1/20 0.31
ABCG2 Q9UNQ0 1/20 0.31
MCL1 Q07820 2/20 0.30
BCL2 P10415 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17012215 0.96 ALDH1A1 (0.34) PRKDCALDH1A1ATMGABRA1GABRG2
SCHEMBL17132480 0.96 PDK2 (0.35) PRKDCALDH1A1ATMGABRA1GABRG2
SCHEMBL16484667 0.96 ABCG2 (0.34) PRKDCALDH1A1ATMGABRA1GABRG2
SCHEMBL23764184 0.95 ALDH1A1 (0.34) PRKDCALDH1A1ATMMEN1KMT2A
SCHEMBL16484677 0.93 ABCG2 (0.35) ALDH1A1ATMMEN1KMT2ACSF1R
SCHEMBL16484684 0.93 ABCG2 (0.35) ALDH1A1ATMMEN1KMT2ACSF1R
SCHEMBL16484413 0.93 ALDH1A1 (0.35) PRKDCALDH1A1ATMGABRA1GABRG2
SCHEMBL17132478 0.92 ADRA2C (0.36) ALDH1A1GABRA1GABRG2GABRB3GABRA5
SCHEMBL16485035 0.91 PRKDC (0.35) PRKDCALDH1A1GABRA1GABRG2GABRB3
SCHEMBL23764343 0.91 TUBB4A (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9935273-B2 Fluoranthene derivative, light-emitting device material containing same, and light-emitting device TORAY INDUSTRIES, INC. (JP) 2018-04-03 US disclosed
US-9935273-B2 Fluoranthene derivative, light-emitting device material containing same, and light-emitting device TORAY INDUSTRIES, INC. (JP) 2018-04-03 US disclosed
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2015-10-01 US disclosed
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2015-10-01 US disclosed
WO-2014057874-A1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT 東レ株式会社 (JP) 2014-04-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE FMNL1, AFF2, LEF1 PRKDC 3703/4885ALDH1A1 1031/4885ATM 4142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.