Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 4/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | CPA1 | P15085 | 2/20 | 0.41 |
| ▸ | CPA3 | P15088 | 2/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | CPB1 | P15086 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17891296 | 0.89 | MMP12 (0.43) | CYP1A2CTSKTHRBACEPPARG | |
| SCHEMBL961985 | 0.84 | CYP1A2 (0.44) | CYP1A2THRBSRRALPIPKM | |
| SCHEMBL9646933 | 0.84 | CTSK (0.47) | CYP1A2CTSKTHRBSRRALPI | |
| SCHEMBL1874095 | 0.84 | PIN1 (0.50) | — | |
| SCHEMBL14673835 | 0.83 | MMP12 (0.47) | THRBPPARGPPARAHCAR2 | |
| SCHEMBL3290998 | 0.83 | ALPI (0.49) | CYP1A2THRBSRRALPIPKM | |
| SCHEMBL27801416 | 0.83 | SRR (0.57) | SRRACEPPARGPPARA | |
| SCHEMBL3296251 | 0.83 | CTSK (0.51) | CTSKTHRBCTSLCTSB | |
| SCHEMBL21351752 | 0.82 | CYP1A2 (0.40) | CYP1A2CTSKSRRALPIPKM | |
| SCHEMBL27741432 | 0.82 | CTSK (0.40) | CTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160194424-A1 | MONOMERS FOR USE IN A POLYMERIZABLE COMPOSITION AND HIGH REFRACTIVE INDEX POLYMER FOR OPTHALMIC APPLICATIONS | CONTAMAC LIMITED (GB) | 2016-07-07 | — | — | US | disclosed |
| US-20160194424-A1 | MONOMERS FOR USE IN A POLYMERIZABLE COMPOSITION AND HIGH REFRACTIVE INDEX POLYMER FOR OPTHALMIC APPLICATIONS | CONTAMAC LIMITED (GB) | 2016-07-07 | — | — | US | disclosed |
| EP-3033366-A1 | MONOMERS FOR USE IN A POLYMERIZABLE COMPOSITION AND HIGH REFRACTIVE INDEX POLYMER FOR OPTHALMIC APPLICATIONS | Contamac Limited (GB) | 2016-06-22 | — | — | EP | disclosed |
| WO-2015022511-A1 | MONOMERS FOR USE IN A POLYMERIZABLE COMPOSITION AND HIGH REFRACTIVE INDEX POLYMER FOR OPTHALMIC APPLICATIONS | CONTAMAC LTD (GB) | 2015-02-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160194424-A1 | MONOMERS FOR USE IN A POLYMERIZABLE COMPOSITION AND HIGH REFRACTIVE INDEX POLYMER FOR OPTHALMIC APPLICATIONS | NR2E3, NR1I2, NR1I3 | CYP1A2 667/4885CTSK 4687/4885THRB 2319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.