Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.95 |
| ▸ | MAPT | P10636 | 8/20 | 0.80 |
| ▸ | NPC1 | O15118 | 4/20 | 0.80 |
| ▸ | RAB9A | P51151 | 4/20 | 0.80 |
| ▸ | KLK7 | P49862 | 1/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.79 |
| ▸ | MEN1 | O00255 | 6/20 | 0.79 |
| ▸ | GAA | P10253 | 1/20 | 0.79 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.69 |
| ▸ | THRB | P10828 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.65 |
| ▸ | RELA | Q04206 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16486232 | 0.88 | KMT2A (0.87) | FAAHMAPTNPC1RAB9AKLK7 | |
| SCHEMBL17318627 | 0.83 | FAAH (0.69) | FAAHMAPTNPC1RAB9AKLK7 | |
| SCHEMBL16486184 | 0.80 | KMT2A (1.00) | FAAHMAPTNPC1RAB9AKMT2A | |
| SCHEMBL17731989 | 0.79 | MAPT (0.67) | FAAHMAPTNPC1KMT2AMEN1 | |
| SCHEMBL15427025 | 0.79 | SMN1; SMN2 (1.00) | FAAHMAPTNPC1RAB9AKLK7 | |
| SCHEMBL13901818 | 0.78 | FAAH (0.61) | FAAHMAPTNPC1RAB9AKMT2A | |
| SCHEMBL6295679 | 0.77 | NPC1 (1.00) | MAPTNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL17732020 | 0.77 | NPC1 (0.74) | FAAHMAPTNPC1RAB9AKMT2A | |
| SCHEMBL15867670 | 0.77 | NPC1 (1.00) | FAAHMAPTNPC1RAB9AKLK7 | |
| SCHEMBL21523629 | 0.77 | SCD5 (1.00) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015021943-A9 | INDUCING NEUROGENESIS BY AXIN ENHANCER | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-12-30 | — | — | WO | disclosed |
| WO-2015021943-A1 | INDUCING NEUROGENESIS BY AXIN ENHANCER | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-02-19 | — | — | WO | disclosed |