Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17868081 | 1.00 | EPHX2 (0.41) | EPHX2ALOX5ALDH1A1LMNACNR1 | |
| SCHEMBL16510911 | 1.00 | EPHX2 (0.41) | EPHX2ALOX5ALDH1A1LMNACNR1 | |
| SCHEMBL16487277 | 0.91 | MAPT (0.43) | ALDH1A1LMNACYP1A2CYP2D6MAPT | |
| SCHEMBL18102172 | 0.85 | ALDH1A1 (0.54) | EPHX2ALOX5ALDH1A1LMNACNR1 | |
| SCHEMBL17879418 | 0.84 | CYP1A2 (0.40) | ALDH1A1LMNACNR1CYP1A2CYP2D6 | |
| SCHEMBL16486838 | 0.82 | HSD17B10 (0.53) | LMNACYP1A2CYP2D6MAPTCYP2C9 | |
| SCHEMBL17868033 | 0.82 | HSD17B10 (0.53) | LMNACYP1A2CYP2D6MAPTCYP2C9 | |
| SCHEMBL18102168 | 0.79 | EPHX2 (0.48) | EPHX2ALOX5ALDH1A1LMNACNR1 | |
| SCHEMBL18102170 | 0.78 | CNR1 (0.53) | ALOX5ALDH1A1CNR1MAPTCNR2 | |
| SCHEMBL23387069 | 0.78 | ALDH1A1 (0.43) | EPHX2ALOX5ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160185735-A1 | FATTY ACID ANALOGS AND THEIR USE | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2016-06-30 | — | — | US | disclosed |
| WO-2015023631-A2 | FATTY ACID ANALOGS AND THEIR USE | ANDERSON CAROLYN (US) | 2015-02-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185735-A1 | FATTY ACID ANALOGS AND THEIR USE | FABP4, ELOVL1, CPT1A | EPHX2 881/4885ALOX5 31/4885ALDH1A1 76/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.