Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | TERT | O14746 | 3/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | FABP4 | P15090 | 2/20 | 0.33 |
| ▸ | F7 | P08709 | 2/20 | 0.33 |
| ▸ | F3 | P13726 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17879416 | 0.91 | MAPT (0.47) | CYP1A2MAPTCYP2C19HSD17B10CYP2C9 | |
| SCHEMBL17868033 | 0.86 | HSD17B10 (0.53) | CYP1A2MAPTCYP2C19HSD17B10CYP2C9 | |
| SCHEMBL16486838 | 0.86 | HSD17B10 (0.53) | CYP1A2MAPTCYP2C19HSD17B10CYP2C9 | |
| SCHEMBL16487372 | 0.84 | EPHX2 (0.41) | CYP1A2MAPTCYP2C19HSD17B10CYP2C9 | |
| SCHEMBL16510911 | 0.84 | EPHX2 (0.41) | CYP1A2MAPTCYP2C19HSD17B10CYP2C9 | |
| SCHEMBL17868081 | 0.84 | EPHX2 (0.41) | CYP1A2MAPTCYP2C19HSD17B10CYP2C9 | |
| SCHEMBL17879415 | 0.84 | HSD17B10 (0.41) | CYP1A2MAPTCYP2C19HSD17B10CYP2C9 | |
| SCHEMBL16510910 | 0.75 | HSD17B10 (0.64) | CYP1A2MAPTCYP2C19HSD17B10CYP2C9 | |
| SCHEMBL14450308 | 0.73 | HSD17B10 (0.61) | CYP1A2MAPTCYP2C19HSD17B10CYP2C9 | |
| SCHEMBL16487277 | 0.73 | MAPT (0.43) | CYP1A2MAPTCYP2C19HSD17B10CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160185735-A1 | FATTY ACID ANALOGS AND THEIR USE | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185735-A1 | FATTY ACID ANALOGS AND THEIR USE | FABP4, ELOVL1, CPT1A | CYP1A2 752/4885MAPT 4417/4885CYP2C19 1454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.