Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 19/20 | 1.00 |
| ▸ | ROCK1 | Q13464 | 17/20 | 1.00 |
| ▸ | PRKACA | P17612 | 2/20 | 0.77 |
| ▸ | PRKACG | P22612 | 2/20 | 0.77 |
| ▸ | PRKACB | P22694 | 2/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30988400 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| SCHEMBL1648236 | 0.89 | ROCK2 (1.00) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| SCHEMBL12779554 | 0.87 | ROCK2 (1.00) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| SCHEMBL1648833 | 0.87 | ROCK1 (1.00) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| SCHEMBL1649575 | 0.85 | ROCK2 (1.00) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| SCHEMBL1648507 | 0.83 | ROCK2 (1.00) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| SCHEMBL12779416 | 0.83 | ROCK2 (0.71) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| SCHEMBL1648874 | 0.82 | ROCK2 (0.73) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| SCHEMBL1647622 | 0.82 | ROCK2 (1.00) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| SCHEMBL1649783 | 0.82 | ROCK2 (0.81) | ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260116879-A1 | AZAINDOLE ROCK INHIBITORS | AVICENNA BIOSCIENCES, INC. (US) | 2026-04-30 | — | — | US | disclosed |
| US-12415805-B2 | Azaindole rock inhibitors | AVICENNA BIOSCIENCES, INC. (US) | 2025-09-16 | — | — | US | disclosed |
| US-20250250273-A1 | AZAINDOLE ROCK INHIBITORS | AVICENNA BIOSCIENCES, INC. (US) | 2025-08-07 | — | — | US | disclosed |
| US-12286433-B1 | Azaindole rock inhibitors | AVICENNA BIOSCIENCES, INC. (US) | 2025-04-29 | — | — | US | disclosed |
| US-12281115-B2 | Azaindole rock inhibitors | AVICENNA BIOSCIENCES, INC. (US) | 2025-04-22 | — | — | US | disclosed |
| US-20250115605-A1 | AZAINDOLE ROCK INHIBITORS | AVICENNA BIOSCIENCES, INC. (US) | 2025-04-10 | — | — | US | disclosed |
| US-20250092038-A1 | AZAINDOLE ROCK INHIBITORS | AVICENNA BIOSCIENCES, INC. (US) | 2025-03-20 | — | — | US | disclosed |
| US-12240848-B2 | Azaindole rock inhibitors | AVICENNA BIOSCIENCES, INC. (US) | 2025-03-04 | — | — | US | disclosed |
| US-12116366-B2 | Azaindole rock inhibitors | AVICENNA BIOSCIENCES, INC. (US) | 2024-10-15 | — | — | US | disclosed |
| US-20240254124-A1 | AZAINDOLE ROCK INHIBITORS | AVICENNA BIOSCIENCES, INC. (US) | 2024-08-01 | — | — | US | disclosed |
| US-20240246972-A1 | AZAINDOLE ROCK INHIBITORS | AVICENNA BIOSCIENCES, INC. (US) | 2024-07-25 | — | — | US | disclosed |
| WO-2024145569-A2 | AZAINDOLE ROCK INHIBITORS | AVICENNA BIOSCIENCES, INC. (US) | 2024-07-04 | — | — | WO | disclosed |
| WO-2024145569-A2 | AZAINDOLE ROCK INHIBITORS | AVICENNA BIOSCIENCES, INC. (US) | 2024-07-04 | — | — | WO | disclosed |
| WO-2011050245-A1 | BICYCLIC HETEROARYLS AS KINASE INHIBITORS | FENG YANGBO (US) | 2011-04-28 | — | — | WO | disclosed |
| WO-2011050245-A1 | BICYCLIC HETEROARYLS AS KINASE INHIBITORS | FENG YANGBO (US) | 2011-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12415805-B2 | Azaindole rock inhibitors | ROCK2, ROCK1, ARHGDIA | ROCK2 1/4885ROCK1 2/4885PRKACA 450/4885 |
| US-20250250273-A1 | AZAINDOLE ROCK INHIBITORS | ROCK2, ROCK1, ARHGDIA | ROCK2 1/4885ROCK1 2/4885PRKACA 450/4885 |
| US-12240848-B2 | Azaindole rock inhibitors | ROCK2, ROCK1, ARHGDIA | ROCK2 1/4885ROCK1 2/4885PRKACA 450/4885 |
| US-12281115-B2 | Azaindole rock inhibitors | ROCK2, ROCK1, ARHGDIA | ROCK2 1/4885ROCK1 2/4885PRKACA 450/4885 |
| US-20240254124-A1 | AZAINDOLE ROCK INHIBITORS | ROCK2, ROCK1, ARHGDIA | ROCK2 1/4885ROCK1 2/4885PRKACA 450/4885 |
| US-20260116879-A1 | AZAINDOLE ROCK INHIBITORS | PRKG2, PRKG1, ROCK2 | ROCK2 3/4885ROCK1 4/4885PRKACA 13/4885 |
| US-12116366-B2 | Azaindole rock inhibitors | ROCK2, ROCK1, ARHGDIA | ROCK2 1/4885ROCK1 2/4885PRKACA 450/4885 |
| US-20250115605-A1 | AZAINDOLE ROCK INHIBITORS | ROCK2, ROCK1, ARHGDIA | ROCK2 1/4885ROCK1 2/4885PRKACA 450/4885 |
| US-12286433-B1 | Azaindole rock inhibitors | ROCK2, ROCK1, ARHGDIA | ROCK2 1/4885ROCK1 2/4885PRKACA 450/4885 |
| US-20240246972-A1 | AZAINDOLE ROCK INHIBITORS | ROCK2, ROCK1, ARHGDIA | ROCK2 1/4885ROCK1 2/4885PRKACA 450/4885 |
| US-20250092038-A1 | AZAINDOLE ROCK INHIBITORS | ROCK2, ROCK1, ARHGDIA | ROCK2 1/4885ROCK1 2/4885PRKACA 450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.