Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR1 | P25024 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.34 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9072457 | 0.79 | CYP1A2 (0.40) | MAPTKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL2668579 | 0.78 | ATM (0.39) | MAPTKMT2AALDH1A1 | |
| SCHEMBL16429390 | 0.77 | HSD17B10 (0.36) | CXCR1CXCR2MAPTPOLBKMT2A | |
| SCHEMBL9072456 | 0.76 | CXCR1 (0.45) | CXCR1CXCR2MAPTL3MBTL1 | |
| SCHEMBL24883553 | 0.75 | ATM (0.45) | CXCR1CXCR2MAPTPOLBKMT2A | |
| SCHEMBL15196329 | 0.75 | ALDH1A1 (0.39) | MAPTPOLBKMT2AALDH1A1HSD17B10 | |
| SCHEMBL14485982 | 0.75 | CXCR1 (0.40) | CXCR1CXCR2MAPTPOLBKMT2A | |
| SCHEMBL23167730 | 0.74 | CXCR1 (0.42) | CXCR1CXCR2MAPTPOLBKMT2A | |
| SCHEMBL24635805 | 0.73 | GSTP1 (0.38) | CXCR1CXCR2MAPTPOLBKMT2A | |
| SCHEMBL9400123 | 0.73 | PTGS1 (0.46) | MAPTPOLBPTGS1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013204-B1 | 2-AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC (US) | 2015-02-18 | — | — | EP | disclosed |