Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR1 | P25024 | 2/20 | 0.45 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TRPC6 | Q9Y210 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | GCK | P35557 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.34 |
| ▸ | SELE | P16581 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2668579 | 0.89 | ATM (0.39) | RAB9ATRPC6MAPTGCK | |
| SCHEMBL15404905 | 0.77 | SLC22A12 (0.39) | CXCR1CXCR2NPC1RAB9AGCK | |
| SCHEMBL2667557 | 0.76 | ATM (0.39) | CXCR1CXCR2RAB9AMAPTGCK | |
| SCHEMBL16488510 | 0.76 | CXCR1 (0.38) | CXCR1CXCR2MAPTL3MBTL1 | |
| SCHEMBL14485982 | 0.74 | CXCR1 (0.40) | CXCR1CXCR2NPC1RAB9ATDP1 | |
| SCHEMBL4072161 | 0.73 | CXCR1 (0.47) | CXCR1CXCR2NPC1RAB9ATDP1 | |
| SCHEMBL9072457 | 0.72 | CYP1A2 (0.40) | RAB9ATDP1MAPTL3MBTL1 | |
| SCHEMBL2668583 | 0.71 | MCL1 (0.42) | NPC1RAB9ATDP1MAPTSMN1; SMN2 | |
| SCHEMBL16429390 | 0.70 | HSD17B10 (0.36) | CXCR1CXCR2RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL15514098 | 0.70 | MEN1 (0.39) | NPC1RAB9ATRPC6LTA4HGCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140073658-A1 | Dipyridylamine Derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-03-13 | — | — | US | disclosed |
| EP-2684878-A1 | DIPYRIDYLAMINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-01-15 | — | — | EP | disclosed |
| WO-2007117381-A9 | 2 -AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC (US) | 2008-03-27 | — | — | WO | disclosed |
| WO-2007117381-A2 | 2 -AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC. (US) | 2007-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140073658-A1 | Dipyridylamine Derivative | GCK, GCKR, GALK1 | CXCR1 4490/4885CXCR2 4213/4885NPC1 3032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.