Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | BRD2 | P25440 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.33 |
| ▸ | TPMT | P51580 | 1/20 | 0.33 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | BAD | Q92934 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16488564 | 0.86 | DHODH (0.42) | BRD4BRD2CREBBPAURKATPX2 | |
| SCHEMBL16488562 | 0.84 | BRD4 (0.43) | BRD4BRD2CREBBPCNR2TPMT | |
| SCHEMBL25551247 | 0.83 | RXRA (0.46) | AURKATPX2TPMTDHODHRXRA | |
| SCHEMBL16488557 | 0.83 | ERN1 (0.34) | BRD4BRD2CREBBPAURKATPX2 | |
| SCHEMBL12349931 | 0.82 | CA12 (0.42) | TPMTMEN1KMT2APLA2G2AAKR1C3 | |
| SCHEMBL16488613 | 0.82 | TPMT (0.46) | CNR2TPMTHCAR1DHODHRXRA | |
| SCHEMBL16488563 | 0.81 | RXRA (0.50) | AURKATPX2DHODHRXRAERN1 | |
| SCHEMBL16488560 | 0.81 | RXRA (0.50) | AURKATPX2DHODHRXRAERN1 | |
| SCHEMBL16769642 | 0.81 | BRD4 (0.41) | BRD4BRD2CREBBPCNR2TPMT | |
| SCHEMBL12384276 | 0.80 | MEN1 (0.44) | TPMTRXRAMEN1KMT2APLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9593132-B2 | Metal-organic frameworks (MOF) for gas capture | THE UNIVERSITY OF NOTTINGHAM (GB) | 2017-03-14 | — | — | US | disclosed |
| US-20150047505-A1 | METAL-ORGANIC FRAMEWORKS (MOF) FOR GAS CAPTURE | THE UNIVERSITY OF NOTTINGHAM (GB) | 2015-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150047505-A1 | METAL-ORGANIC FRAMEWORKS (MOF) FOR GAS CAPTURE | HAO2, TRPM6, FTH1 | BRD4 4568/4885BRD2 4398/4885CREBBP 4699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.