Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 5/20 | 0.50 |
| ▸ | DHODH | Q02127 | 3/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 2/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | CYCS | P99999 | 1/20 | 0.40 |
| ▸ | FABP1 | P07148 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16488560 | 1.00 | RXRA (0.50) | RXRADHODHAURKATPX2RXRB | |
| SCHEMBL15119805 | 0.97 | RXRA (0.56) | RXRADHODHRXRBERN1TRIM24 | |
| SCHEMBL16488564 | 0.94 | DHODH (0.42) | RXRADHODHAURKATPX2LMNA | |
| SCHEMBL14680854 | 0.91 | RXRA (0.54) | RXRADHODHAURKATPX2RXRB | |
| SCHEMBL25551247 | 0.91 | RXRA (0.46) | RXRADHODHAURKATPX2LMNA | |
| SCHEMBL16559878 | 0.89 | CTRC (0.43) | RXRADHODHAURKATPX2ERN1 | |
| SCHEMBL16559873 | 0.89 | HSD17B1 (0.42) | RXRADHODHAURKATPX2RXRB | |
| SCHEMBL12349931 | 0.87 | CA12 (0.42) | LMNA | |
| SCHEMBL15119807 | 0.86 | RXRA (0.51) | RXRADHODHAURKATPX2RXRB | |
| SCHEMBL14680895 | 0.85 | RXRA (0.46) | RXRADHODHRXRBFABP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9593132-B2 | Metal-organic frameworks (MOF) for gas capture | THE UNIVERSITY OF NOTTINGHAM (GB) | 2017-03-14 | — | — | US | disclosed |
| US-20150047505-A1 | METAL-ORGANIC FRAMEWORKS (MOF) FOR GAS CAPTURE | THE UNIVERSITY OF NOTTINGHAM (GB) | 2015-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150047505-A1 | METAL-ORGANIC FRAMEWORKS (MOF) FOR GAS CAPTURE | HAO2, TRPM6, FTH1 | RXRA 2096/4885DHODH 641/4885AURKA 649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.