Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | POLA1 | P09884 | 1/20 | 0.35 |
| ▸ | POLD1 | P28340 | 1/20 | 0.35 |
| ▸ | P2RY2 | P41231 | 14/20 | 0.35 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.35 |
| ▸ | P2RY4 | P51582 | 5/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25141885 | 0.85 | P2RY2 (0.37) | POLBPOLA1POLD1P2RY2P2RY6 | |
| SCHEMBL22327375 | 0.84 | POLB (0.39) | POLBPOLA1POLD1P2RY2P2RY6 | |
| SCHEMBL21506757 | 0.84 | POLB (0.39) | POLBPOLA1POLD1P2RY2P2RY6 | |
| SCHEMBL271833 | 0.83 | P2RY2 (0.37) | POLBPOLA1POLD1P2RY2P2RY6 | |
| SCHEMBL22778271 | 0.82 | POLB (0.38) | POLBPOLA1POLD1P2RY2P2RY6 | |
| SCHEMBL18462928 | 0.82 | P2RY2 (0.37) | POLBPOLA1POLD1P2RY2P2RY6 | |
| SCHEMBL21555520 | 0.82 | P2RY2 (0.37) | POLBPOLA1POLD1P2RY2P2RY6 | |
| SCHEMBL21555519 | 0.82 | P2RY2 (0.37) | POLBPOLA1POLD1P2RY2P2RY6 | |
| SCHEMBL22002630 | 0.82 | P2RY2 (0.37) | POLBPOLA1POLD1P2RY2P2RY6 | |
| SCHEMBL24023275 | 0.81 | POLA1 (0.37) | POLBPOLA1POLD1P2RY2P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210062186-A1 | NEXT-GENERATION SEQUENCING LIBRARIES | ABBOTT MOLECULAR INC. | 2021-03-04 | — | — | US | disclosed |
| US-10865410-B2 | Next-generation sequencing libraries | ABBOTT MOLECULAR INC. (US) | 2020-12-15 | — | — | US | disclosed |
| US-20150050697-A1 | NUCLEOTIDE ANALOGS | ABBOTT MOLECULAR INC. | 2015-02-19 | — | — | US | disclosed |
| US-20150051116-A1 | NEXT-GENERATION SEQUENCING LIBRARIES | ABBOTT MOLECULAR INC. | 2015-02-19 | — | — | US | disclosed |
| US-20150051088-A1 | NEXT-GENERATION SEQUENCING LIBRARIES | ABBOTT MOLECULAR INC. | 2015-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150050697-A1 | NUCLEOTIDE ANALOGS | NUDT1, NT5C3B, RNGTT | POLB 32/4885POLA1 159/4885POLD1 361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.