Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 2/20 | 0.58 |
| ▸ | CTSL | P07711 | 2/20 | 0.58 |
| ▸ | TTR | P02766 | 1/20 | 0.57 |
| ▸ | DHODH | Q02127 | 1/20 | 0.52 |
| ▸ | FABP4 | P15090 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MYC | P01106 | 1/20 | 0.49 |
| ▸ | MAX | P61244 | 1/20 | 0.49 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.48 |
| ▸ | PAK4 | O96013 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | RET | P07949 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1446469 | 0.84 | TTR (0.71) | TTRDHODHFABP4AKR1C3AKR1C2 | |
| SCHEMBL4246352 | 0.82 | CTSV (0.70) | CTSVCTSLFABP4AKR1C3AKR1C2 | |
| SCHEMBL9551973 | 0.80 | CTSV (0.71) | CTSVCTSLFABP4AKR1C3AKR1C2 | |
| SCHEMBL4251354 | 0.80 | CTSV (0.71) | CTSVCTSLFABP4AKR1C3AKR1C2 | |
| SCHEMBL16489011 | 0.77 | MYC (0.60) | CTSVCTSLTTRAKR1C3AKR1C2 | |
| SCHEMBL16489006 | 0.76 | SLC25A1 (0.65) | CTSVCTSLTTRFABP4AKR1C3 | |
| SCHEMBL22720195 | 0.76 | CTSV (0.78) | CTSVCTSLAKR1C3AKR1C2MEN1 | |
| SCHEMBL22720115 | 0.76 | MYC (0.65) | CTSVCTSLFABP4AKR1C3AKR1C2 | |
| SCHEMBL28133218 | 0.76 | FABP4 (0.75) | CTSVCTSLTTRFABP4AKR1C3 | |
| SCHEMBL3681838 | 0.76 | NPC1 (0.71) | CTSVCTSLTTRDHODHFABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150051286-A1 | ANTHRANILIC ACID DERIVATIVES: NOVEL INHIBITORS OF ADVANCED GLYCATION END-PRODUCTS (AGES) FORMATION | CHOUDHARY MUHAMMAD IQBAL (PK) | 2015-02-19 | — | — | US | disclosed |
| US-20150051286-A1 | ANTHRANILIC ACID DERIVATIVES: NOVEL INHIBITORS OF ADVANCED GLYCATION END-PRODUCTS (AGES) FORMATION | CHOUDHARY MUHAMMAD IQBAL (PK) | 2015-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150051286-A1 | ANTHRANILIC ACID DERIVATIVES: NOVEL INHIBITORS OF ADVANCED GLYCATION END-PRODUCTS (AGES) FORMATION | AGER, NFKBIA, DNPEP | CTSV 1340/4885CTSL 970/4885TTR 843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.