SCHEMBL16490260

SCHEMBL16490260

O=S(=O)(O)c1cccc2c(/N=N/c3ccc(/N=N/c4ccccc4)c4ccccc34)ccc(Nc3ccccc3)c12

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 0.66
▸ KMT2A Q03164 3/20 0.66
▸ THRB P10828 1/20 0.66
▸ SNCA P37840 2/20 0.65
▸ CHAT P28329 1/20 0.65
▸ TTR P02766 1/20 0.59
▸ FABP4 P15090 1/20 0.59
▸ CCNA2 P20248 1/20 0.59
▸ CDK2 P24941 1/20 0.59
▸ MAPK14 Q16539 1/20 0.59
▸ NR4A1 P22736 1/20 0.57
▸ ATIC P31939 2/20 0.48
▸ CYP1A2 P05177 2/20 0.47
▸ SENP2 Q9HC62 4/20 0.46
▸ SENP1 Q9P0U3 4/20 0.46
▸ SUMO2 P61956 3/20 0.46
▸ SUMO1 P63165 3/20 0.46
▸ SENP7 Q9BQF6 3/20 0.46
▸ SENP3 Q9H4L4 3/20 0.44
▸ L3MBTL1 Q9Y468 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15276170 0.93 MEN1 (0.67) MEN1KMT2ATHRBSNCACHAT
SCHEMBL12177978 0.92 MEN1 (0.68) MEN1KMT2ATHRBSNCACHAT
SCHEMBL15276051 0.91 KMT2A (0.71) MEN1KMT2ATHRBSNCACHAT
SCHEMBL29401264 0.91 KMT2A (0.71) MEN1KMT2ATHRBSNCACHAT
SCHEMBL29501265 0.91 MEN1 (0.69) MEN1KMT2ATHRBSNCACHAT
SCHEMBL28414211 0.90 KMT2A (0.69) MEN1KMT2ATHRBSNCACHAT
SCHEMBL15274126 0.90 MEN1 (0.60) MEN1KMT2ATHRBSNCACHAT
SCHEMBL15276008 0.89 MEN1 (0.67) MEN1KMT2ATHRBSNCACHAT
SCHEMBL12177967 0.89 MEN1 (0.67) MEN1KMT2ATHRBSNCACHAT
SCHEMBL11849151 0.88 MEN1 (0.61) MEN1KMT2ATHRBSNCACHAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9364403-B2 Hair treatment methods PERACHEM LIMITED (GB) 2016-06-14 — — US disclosed
US-9320695-B2 Hair treatment methods PERACHEM LIMITED (GB) 2016-04-26 — — US disclosed
US-20150068548-A1 Hair Treatment Methods HSNF LIMITED (GB) 2015-03-12 — — US disclosed
US-20150047131-A1 Hair Treatment Methods HSNF LIMITED (GB) 2015-02-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150068548-A1 Hair Treatment Methods TST, OAT, SLC14A1 MEN1 3002/4885KMT2A 2377/4885THRB 2423/4885
US-20150047131-A1 Hair Treatment Methods POLR1C, SHH, DNMT3A MEN1 2294/4885KMT2A 372/4885THRB 2412/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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