Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | BMP1 | P13497 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16470411 | 0.85 | L3MBTL1 (0.38) | MEN1KMT2ABMP1L3MBTL1TDP1 | |
| SCHEMBL16469858 | 0.68 | MAPT (0.42) | MEN1KMT2AL3MBTL1LMNAMAPT | |
| SCHEMBL16470365 | 0.65 | MAPT (0.39) | MEN1KMT2AL3MBTL1TDP1LMNA | |
| SCHEMBL16469751 | 0.65 | MAPT (0.41) | MEN1KMT2AL3MBTL1TDP1LMNA | |
| SCHEMBL30154405 | 0.65 | MAPT (0.39) | MEN1KMT2AL3MBTL1TDP1LMNA | |
| SCHEMBL16470696 | 0.65 | MAPT (0.39) | MEN1KMT2AL3MBTL1TDP1LMNA | |
| SCHEMBL16469705 | 0.65 | TXNRD1 (0.43) | MEN1KMT2ALMNAMAPTS1PR1 | |
| SCHEMBL29371318 | 0.65 | TXNRD1 (0.43) | MEN1KMT2ALMNAMAPTS1PR1 | |
| SCHEMBL281998 | 0.64 | — | — | |
| SCHEMBL16470208 | 0.63 | MAPT (0.41) | MEN1KMT2AL3MBTL1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9386769-B2 | Thiazole methylamino pyridine compounds and preparation method therefor | HUNAN RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) | 2016-07-12 | — | — | US | disclosed |
| US-20150051402-A1 | Thiazole Methylamino Pyridine Compounds and Preparation Method Therefor | HUNAN RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) | 2015-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150051402-A1 | Thiazole Methylamino Pyridine Compounds and Preparation Method Therefor | NOTUM, WEE1, CYP51A1 | MEN1 1003/4885KMT2A 1522/4885BMP1 3944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.