SCHEMBL16469705

SCHEMBL16469705

CCN(Cc1cnc(Cl)s1)c1nc(OC)ccc1[N+](=O)[O-]

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TXNRD1 Q16881 13/20 0.43
MAPT P10636 3/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
LMNA P02545 1/20 0.41
PKM P14618 1/20 0.41
KMT2A Q03164 1/20 0.41
JAK2 O60674 1/20 0.40
S1PR4 O95977 1/20 0.40
HSP90AA1 P07900 1/20 0.40
S1PR1 P21453 1/20 0.40
MAPK1 P28482 1/20 0.40
HTT P42858 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
GSR P00390 2/20 0.39
POLB P06746 1/20 0.39
GAA P10253 1/20 0.39
RECQL P46063 1/20 0.38
XDH P47989 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29371318 1.00 TXNRD1 (0.43) TXNRD1MAPTKDM4EMEN1LMNA
SCHEMBL16469877 0.92 TXNRD1 (0.41) TXNRD1MAPTKDM4EMEN1LMNA
SCHEMBL16469751 0.92 MAPT (0.41) TXNRD1MAPTKDM4EMEN1LMNA
SCHEMBL16470338 0.90 MAPT (0.40) TXNRD1MAPTKDM4EMEN1LMNA
SCHEMBL29064660 0.89 TXNRD1 (0.43) TXNRD1MAPTS1PR4S1PR1MAPK1
SCHEMBL29878520 0.89 TXNRD1 (0.43) TXNRD1MAPTJAK2S1PR4HSP90AA1
SCHEMBL16469819 0.89 TXNRD1 (0.43) TXNRD1MAPTJAK2S1PR4HSP90AA1
SCHEMBL28454828 0.89 POLB (0.41) TXNRD1MAPTKDM4EMEN1LMNA
SCHEMBL29064663 0.88 TXNRD1 (0.42) TXNRD1MAPTS1PR4S1PR1MAPK1
SCHEMBL29064687 0.88 TXNRD1 (0.39) TXNRD1MAPTJAK2S1PR4HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9386769-B2 Thiazole methylamino pyridine compounds and preparation method therefor HUNAN RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) 2016-07-12 US claimed
US-20150051402-A1 Thiazole Methylamino Pyridine Compounds and Preparation Method Therefor HUNAN RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) 2015-02-19 US claimed
EP-3778583-B1 HETEROCYCLIC COMPOUND AND ARTHROPOD PEST CONTROL COMPOSITION CONTAINING SAME SUMITOMO CHEMICAL CO (JP) 2025-06-18 EP disclosed
EP-3733667-B1 HETEROCYCLIC COMPOUNDS AND NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING SAME SUMITOMO CHEMICAL CO (JP) 2024-06-12 EP disclosed
US-20240150312-A1 PYRAZINE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-05-09 US disclosed
CN-111770923-B Heterocyclic compound and harmful arthropod control agent containing same 住友化学株式会社 2024-04-09 CN disclosed
CN-110719907-B Heterocyclic compound and composition containing same 住友化学株式会社 2024-04-05 CN disclosed
CN-110461834-B Condensed heterocyclic compound and composition containing same 住友化学株式会社 2024-03-12 CN disclosed
US-11905271-B2 Pyrazine compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-02-20 US disclosed
CN-117561250-A Heterocyclic compound and harmful arthropod control composition containing same 住友化学株式会社 2024-02-13 CN disclosed
CN-117545356-A Heterocyclic compound and method for controlling drug-resistant harmful arthropods by using composition containing same 住友化学株式会社 2024-02-09 CN disclosed
US-9386769-B2 Thiazole methylamino pyridine compounds and preparation method therefor HUNAN RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) 2016-07-12 US disclosed
US-9386769-B2 Thiazole methylamino pyridine compounds and preparation method therefor HUNAN RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) 2016-07-12 US disclosed
US-9386769-B2 Thiazole methylamino pyridine compounds and preparation method therefor HUNAN RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) 2016-07-12 US disclosed
CN-104770374-A Bactericidal composition HUNAN CHEMICAL INDUSTRY INST CO LTD 2015-07-15 CN disclosed
CN-104770374-A Bactericidal composition HUNAN CHEMICAL INDUSTRY INST CO LTD 2015-07-15 CN disclosed
CN-104387377-A Preparation method of thiazole methylamino pyridine compound HUNAN HAILI CHANGDE PESTICIDE & CHEMICAL INDUSTRY CO LTD 2015-03-04 CN disclosed
US-20150051402-A1 Thiazole Methylamino Pyridine Compounds and Preparation Method Therefor HUNAN RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) 2015-02-19 US disclosed
US-20150051402-A1 Thiazole Methylamino Pyridine Compounds and Preparation Method Therefor HUNAN RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) 2015-02-19 US disclosed
US-20150051402-A1 Thiazole Methylamino Pyridine Compounds and Preparation Method Therefor HUNAN RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) 2015-02-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150051402-A1 Thiazole Methylamino Pyridine Compounds and Preparation Method Therefor NOTUM, WEE1, CYP51A1 TXNRD1 1289/4885MAPT 2642/4885KDM4E 1004/4885
US-20240150312-A1 PYRAZINE COMPOUND PPOX, NOX5, NISCH TXNRD1 1637/4885MAPT 3332/4885KDM4E 2245/4885
US-11905271-B2 Pyrazine compound MORF4L1, DPY30, RPL30 TXNRD1 1955/4885MAPT 3293/4885KDM4E 1807/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.