SCHEMBL16492040

SCHEMBL16492040

CC(C)(C)c1ccc2nc(CCl)ccc2c1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ BACE1 P56817 1/20 0.38
▸ SCN10A Q9Y5Y9 7/20 0.37
▸ KCNH2 Q12809 1/20 0.37
▸ KMT2A Q03164 3/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ PDE10A Q9Y233 1/20 0.36
▸ PON1 P27169 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.33
▸ HPGD P15428 1/20 0.33
▸ ALOX15 P16050 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ METAP2 P50579 1/20 0.33
▸ NPSR1 Q6W5P4 1/20 0.33
▸ NR1I2 O75469 1/20 0.32
▸ MCHR1 Q99705 1/20 0.32
▸ CYP1A2 P05177 2/20 0.32
▸ CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10222604 0.84 BACE1 (0.39) BACE1SCN10AKCNH2KMT2AMEN1
SCHEMBL6754978 0.83 BACE1 (0.57) BACE1KCNH2PDE10AMETAP2MCHR1
SCHEMBL29485681 0.79 MEN1 (0.38) BACE1SCN10AKCNH2KMT2AMEN1
SCHEMBL16492037 0.79 MEN1 (0.38) BACE1SCN10AKCNH2KMT2AMEN1
SCHEMBL12025091 0.77 BACE1 (0.44) BACE1SCN10AKCNH2KMT2AMEN1
SCHEMBL1724199 0.77 CYP1A2 (0.57) BACE1KMT2AMEN1ALDH1A1HPGD
SCHEMBL10182842 0.74 CYP1A2 (0.59) BACE1SCN10AKCNH2KMT2AMEN1
SCHEMBL2704185 0.74 KCNH2 (0.42) BACE1SCN10AKCNH2KMT2AMEN1
SCHEMBL2412433 0.74 HDAC1 (0.47) BACE1KMT2APDE10ANPSR1
SCHEMBL2921137 0.73 PLAU (0.57) BACE1KCNH2KMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559675-B2 Resin composition and molded object DIC CORPORATION (JP) 2026-02-24 — — US disclosed
US-20250179256-A1 MASTERBATCH, RESIN COMPOSITION INCLUDING SAME, AND METHOD FOR PRODUCING MOLDED OBJECT DIC CORPORATION (JP) 2025-06-05 — — US disclosed
US-20250051638-A1 POWDERED FLUOROCHROME COMPOSITION, RESIN COMPOSITION, MOLDED ARTICLE, AND METHOD FOR PRODUCING POWDERED FLUOROCHROME COMPOSITION DIC CORPORATION (JP) 2025-02-13 — — US disclosed
EP-4497774-A1 MASTERBATCH, RESIN COMPOSITION INCLUDING SAME, AND METHOD FOR PRODUCING MOLDED OBJECT DIC Corporation (JP) 2025-01-29 — — EP disclosed
CN-118871508-A Masterbatch, resin composition using same, and method for producing molded article DIC株式会社 2024-10-29 — — CN disclosed
CN-118434822-A Powdery pigment composition, method for producing powdery pigment composition, resin composition, and molded article DIC株式会社 2024-08-02 — — CN disclosed
US-20240034927-A1 RESIN COMPOSITION AND MOLDED OBJECT DIC CORPORATION (JP) 2024-02-01 — — US disclosed
WO-2023182121-A1 MASTERBATCH, RESIN COMPOSITION INCLUDING SAME, AND METHOD FOR PRODUCING MOLDED OBJECT DIC株式会社 2023-09-28 — — WO disclosed
EP-4215574-A1 RESIN COMPOSITION AND MOLDED OBJECT DIC Corporation (JP) 2023-07-26 — — EP disclosed
EP-4215574-A1 RESIN COMPOSITION AND MOLDED OBJECT DIC Corporation (JP) 2023-07-26 — — EP disclosed
US-20160271273-A1 RESIN COMPOSITION AND MOLDED ARTICLE DIC CORPORATION (JP) 2016-09-22 — — US disclosed
US-20160271273-A1 RESIN COMPOSITION AND MOLDED ARTICLE DIC CORPORATION (JP) 2016-09-22 — — US disclosed
US-20160271273-A1 RESIN COMPOSITION AND MOLDED ARTICLE DIC CORPORATION (JP) 2016-09-22 — — US disclosed
WO-2016132597-A1 RESIN COMPOSITION AND MOLDED BODY DIC株式会社 2016-08-25 — — WO disclosed
EP-3059288-A1 RESIN COMPOSITION AND MOLDED ARTICLE DIC Corporation (JP) 2016-08-24 — — EP disclosed
US-20160200970-A1 RESIN COMPOSITION AND MOLDED ARTICLE NATIONAL UNIVERSITY CORPORATION KOCHI UNIVERSITY (JP) 2016-07-14 — — US disclosed
US-20160200970-A1 RESIN COMPOSITION AND MOLDED ARTICLE NATIONAL UNIVERSITY CORPORATION KOCHI UNIVERSITY (JP) 2016-07-14 — — US disclosed
US-20160200970-A1 RESIN COMPOSITION AND MOLDED ARTICLE NATIONAL UNIVERSITY CORPORATION KOCHI UNIVERSITY (JP) 2016-07-14 — — US disclosed
EP-3034580-A1 RESIN COMPOSITION AND MOLDED ARTICLE DIC Corporation (JP) 2016-06-22 — — EP disclosed
WO-2015022977-A1 RESIN COMPOSITION AND MOLDED ARTICLE DIC株式会社 (JP) 2015-02-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559675-B2 Resin composition and molded object RER1, MAPRE1, MAPRE2 BACE1 4054/4885SCN10A 4188/4885KCNH2 2657/4885
US-20160271273-A1 RESIN COMPOSITION AND MOLDED ARTICLE IK, CBR3, RER1 BACE1 3851/4885SCN10A 3944/4885KCNH2 1655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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