Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 0.72 |
| ▸ | PDE4A | P27815 | 3/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.72 |
| ▸ | ACHE | P22303 | 2/20 | 0.72 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.72 |
| ▸ | ESR1 | P03372 | 1/20 | 0.72 |
| ▸ | BLM | P54132 | 1/20 | 0.72 |
| ▸ | ADORA2B | P29275 | 9/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.63 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.63 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | TNF | P01375 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10967382 | 0.90 | MAPK1 (0.82) | RXFP1MAPK1LMNAPDE4ACYP1A2 | |
| SCHEMBL7802032 | 0.90 | PDE4A (0.88) | RXFP1MAPK1LMNAPDE4ACYP1A2 | |
| SCHEMBL10855428 | 0.89 | RXFP1 (0.81) | RXFP1MAPK1LMNAPDE4ACYP1A2 | |
| SCHEMBL16120975 | 0.89 | ADORA2B (0.88) | RXFP1MAPK1LMNAACHEMAPT | |
| SCHEMBL11458743 | 0.88 | RXFP1 (0.79) | RXFP1MAPK1LMNAPDE4ACYP1A2 | |
| SCHEMBL4270912 | 0.88 | RXFP1 (0.79) | RXFP1MAPK1LMNAPDE4ACYP1A2 | |
| SCHEMBL10784282 | 0.87 | PDE4A (0.80) | RXFP1MAPK1LMNAPDE4ACYP1A2 | |
| SCHEMBL9682866 | 0.87 | RXFP1 (0.77) | RXFP1MAPK1LMNAPDE4ACYP1A2 | |
| SCHEMBL16120999 | 0.87 | ADORA2B (0.85) | RXFP1MAPK1LMNAMAPTADORA2B | |
| SCHEMBL16121000 | 0.87 | ADORA2B (0.85) | RXFP1MAPK1LMNAMAPTADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | claimed |
| US-20100226943-A1 | SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL | UNIVERSITY OF FLORIDA (US) | 2010-09-09 | — | — | US | claimed |
| CN-101330905-A | Freeze-drying process and products obtained thereby | SCIDOSE LLC (US) | 2008-12-24 | — | — | CN | claimed |
| EP-1954244-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | Scidose, Llc (US) | 2008-08-13 | — | — | EP | claimed |
| WO-2007061529-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | SCIDOSE LLC. (US) | 2007-05-31 | — | — | WO | claimed |
| US-20070116729-A1 | Lyophilization process and products obtained thereby | SCIDOSE LLC | 2007-05-24 | — | — | US | claimed |
| EP-0564461-B1 | THE USE OF ANTIBODIES TO TNF OR FRAGMENTS DERIVED THEREOF AND XANTHINE DERIVATIVES FOR COMBINATION THERAPY AND COMPOSITIONS THEREFOR | CELLTECH THERAPEUTICS LTD (GB) | 1997-01-02 | — | — | EP | claimed |
| EP-0305743-B1 | PHARMACEUTICAL MIXTURE PREPARATION, ITS MANUFACTURE AND USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-11-04 | — | — | EP | claimed |
| US-5118500-A | Side effect reduction when administering a xanthine derivative | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | claimed |
| WO-1992007585-A1 | THE USE OF ANTIBODIES TO TNF OR FRAGMENTS DERIVED THEREOF AND XANTHINE DERIVATIVES FOR COMBINATION THERAPY AND COMPOSITIONS THEREFOR | CELLTECH LIMITED (GB) | 1992-05-14 | — | — | WO | claimed |
| CN-1057390-A | Contain the medicine composition of cephalosporin and xanthine derivative and their purposes | HOECHST AG (DE) | 1992-01-01 | — | — | CN | claimed |
| EP-0462506-A1 | Pharmaceutical preparations of mixtures comprising cefotaxim and derivatives of xanthine and their use | Schrinner, Elmar J., Dr. (DE) | 1991-12-27 | — | — | EP | claimed |
| CN-1014024-B | PROCESS FOR PREPARING PHARMACEUTICALS-FORMULATION | HOECHST AG (DE) | 1991-09-25 | — | — | CN | claimed |
| EP-0169466-B1 | MIXTURE OF XANTHIN DERIVATIVES AND O-ACETYL-SALICYLIC ACID, OR THEIR PHARMACOLOGICALLY ACCEPTABLE SALTS, AND ITS USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-04-04 | — | — | EP | claimed |
| US-4880791-A | BLOOD DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-11-14 | — | — | US | claimed |
| EP-0305743-A2 | Pharmaceutical mixture preparation, its manufacture and use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-03-08 | — | — | EP | claimed |
| CN-1031184-A | Pharmaceutical composition and preparation thereof and application | HOECHST AG (DE) | 1989-02-22 | — | — | CN | claimed |
| CN-85106465-A | A kind of preparation process of pharmaceutical preparation | — | 1986-10-29 | — | — | CN | claimed |
| EP-0169466-A2 | Mixture of xanthin derivatives and O-acetyl-salicylic acid, or their pharmacologically acceptable salts, and its use | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-01-29 | — | — | EP | claimed |
| US-4189469-A | Pharmaceutical compositions | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-02-19 | — | — | US | claimed |