Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 7/20 | 0.52 |
| ▸ | GABRA2 | P47869 | 7/20 | 0.52 |
| ▸ | ACP1 | P24666 | 3/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16494482 | 0.82 | GABRA1 (0.56) | GABRA1GABRA2GABRPGABRDGABRB1 | |
| SCHEMBL16495207 | 0.79 | GABRA1 (0.53) | GABRA1GABRA2GABRPGABRDGABRB1 | |
| SCHEMBL3650747 | 0.74 | GABRA1 (0.52) | GABRA1GABRA2GABRPGABRDGABRB1 | |
| SCHEMBL16495327 | 0.72 | GABRA1 (0.59) | GABRA1GABRA2TLR7ADORA3 | |
| SCHEMBL16494366 | 0.70 | GABRA1 (0.55) | GABRA1GABRA2TLR7ADORA3TP53 | |
| SCHEMBL8466205 | 0.69 | ACP1 (0.42) | ACP1CXCR3TP53NPBWR1 | |
| SCHEMBL16494929 | 0.69 | GABRA1 (0.56) | GABRA1GABRA2TLR7ADORA3TP53 | |
| SCHEMBL18164596 | 0.68 | MAOB (0.70) | — | |
| SCHEMBL16495243 | 0.68 | GABRA1 (0.44) | GABRA1GABRA2TLR7ADORA3TP53 | |
| SCHEMBL8324351 | 0.67 | MAPT (0.46) | CXCR3NPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110294799-A1 | Organic Compounds | NOVARTIS AG | 2011-12-01 | — | — | US | disclosed |
| EP-2188285-A1 | PYRAZOLOQUINOLINE AND PYRAZOLONAPHTHYRIDINE DERIVATIVES AS GABA ALPHA LIGANDS | Novartis Ag (CH) | 2010-05-26 | — | — | EP | disclosed |
| WO-2009021961-A1 | PYRAZOLOQUINOLINE AND PYRAZOLONAPHTHYRIDINE DERIVATIVES AS GABA ALPHA LIGANDS | NOVARTIS AG (CH) | 2009-02-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294799-A1 | Organic Compounds | SLCO4C1, SLCO1B1, SLCO1B3 | GABRA1 446/4885GABRA2 654/4885ACP1 3034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.