Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 3/20 | 0.75 |
| ▸ | ROCK2 | O75116 | 14/20 | 0.62 |
| ▸ | ROCK1 | Q13464 | 7/20 | 0.62 |
| ▸ | PRKACA | P17612 | 4/20 | 0.59 |
| ▸ | PRKACG | P22612 | 4/20 | 0.59 |
| ▸ | PRKACB | P22694 | 4/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1648864 | 0.87 | ROCK2 (0.62) | CLK1ROCK2ROCK1PRKACAPRKACG | |
| SCHEMBL1648112 | 0.84 | ROCK2 (0.61) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| SCHEMBL1649594 | 0.82 | ROCK2 (0.62) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| SCHEMBL3812995 | 0.80 | ROCK2 (0.76) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| SCHEMBL1647581 | 0.79 | ROCK2 (0.64) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| SCHEMBL23384934 | 0.79 | PRKACA (0.66) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| SCHEMBL1648098 | 0.79 | ROCK2 (0.55) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| SCHEMBL1648795 | 0.78 | ROCK2 (0.68) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| SCHEMBL18685145 | 0.77 | ROCK2 (0.81) | ROCK2ROCK1PRKACAPRKACGPRKACB | |
| SCHEMBL15968147 | 0.77 | ROCK2 (1.00) | ROCK2ROCK1PRKACAPRKACGPRKACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050245-A1 | BICYCLIC HETEROARYLS AS KINASE INHIBITORS | FENG YANGBO (US) | 2011-04-28 | — | — | WO | disclosed |
| WO-2011050245-A1 | BICYCLIC HETEROARYLS AS KINASE INHIBITORS | FENG YANGBO (US) | 2011-04-28 | — | — | WO | disclosed |