SCHEMBL16497342

SCHEMBL16497342

CCCCCO[Si](CC(C)C)(OC)OCCCCC

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
LPAR2 Q9HBW0 6/20 0.31
LPAR3 Q9UBY5 6/20 0.31
LPAR6 P43657 3/20 0.31
LPAR1 Q92633 3/20 0.31
LPAR4 Q99677 3/20 0.31
LPAR5 Q9H1C0 3/20 0.31
DNM1 Q05193 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16496643 0.96 LMNA (0.35) LMNALPAR2LPAR3LPAR6LPAR1
SCHEMBL16496925 0.94 LMNA (0.32) LMNA
SCHEMBL16497337 0.90 LMNA (0.32) LMNA
SCHEMBL20448337 0.88 LPAR3 (0.38) LPAR2LPAR3LPAR1DNM1
SCHEMBL8680466 0.88 LPAR3 (0.38) LPAR2LPAR3LPAR1DNM1
SCHEMBL2398601 0.83 ADRB2 (0.35)
SCHEMBL16497409 0.81
SCHEMBL16497412 0.80 LPAR3 (0.31) LPAR2LPAR3LPAR1DNM1
SCHEMBL27955448 0.79 LMNA (0.39) LMNALPAR2LPAR3LPAR1
SCHEMBL1608805 0.79 LMNA (0.39) LMNALPAR2LPAR3LPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110313184-A1 INSULATING FILM MATERIAL, AND FILM FORMATION METHOD UTILIZING THE MATERIAL, AND INSULATING FILM TAIYO NIPPON SANSO CORPORATION (JP) 2011-12-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110313184-A1 INSULATING FILM MATERIAL, AND FILM FORMATION METHOD UTILIZING THE MATERIAL, AND INSULATING FILM APOB, HMGCR, SREBF1 LMNA 158/4885LPAR2 4275/4885LPAR3 3433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.