Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | CA9 | Q16790 | 4/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8680466 | 1.00 | LPAR3 (0.38) | LPAR3LPAR2DNM1THRBTSHR | |
| SCHEMBL2398601 | 0.91 | ADRB2 (0.35) | TSHR | |
| SCHEMBL16496643 | 0.88 | LMNA (0.35) | LPAR3LPAR2DNM1LPAR1 | |
| SCHEMBL16497342 | 0.88 | LMNA (0.35) | LPAR3LPAR2DNM1LPAR1 | |
| SCHEMBL17686048 | 0.85 | S1PR2 (0.38) | DNM1HTTMAPTSPHK1 | |
| SCHEMBL375976 | 0.85 | LPAR2 (0.33) | LPAR3LPAR2 | |
| SCHEMBL11811652 | 0.83 | LPAR3 (0.35) | LPAR3LPAR2DNM1THRBTSHR | |
| SCHEMBL2336204 | 0.83 | LPAR3 (0.35) | LPAR3LPAR2DNM1THRBTSHR | |
| SCHEMBL11803478 | 0.83 | LPAR3 (0.35) | LPAR3LPAR2DNM1THRBTSHR | |
| SCHEMBL5670314 | 0.82 | LPAR3 (0.34) | LPAR3LPAR2DNM1THRBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3356444-A1 | ISOCYANATOALKYL ALKOXYSILANE ADDUCTS MODIFIED BY SILICONE RESINS AND THE USE THEREOF | Evonik Degussa GmbH (DE) | 2018-08-08 | — | — | EP | disclosed |