Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51509 | 0.71 | RXFP1 (0.79) | HPGDKMT2AMEN1MAPTMAPK1 | |
| SCHEMBL9418310 | 0.71 | RXFP1 (0.79) | HPGDKMT2AMEN1MAPTMAPK1 | |
| SCHEMBL6641316 | 0.70 | OAT (0.37) | LMNAALDH1A1CYP1A2BLM | |
| SCHEMBL14040096 | 0.68 | CES2 (0.52) | HPGDKMT2AMEN1MAPTLMNA | |
| Ethyne SCHEMBL8195983 | 0.67 | RXFP1 (0.73) | HPGDKMT2AMEN1MAPTMAPK1 | |
| SCHEMBL17236569 | 0.67 | MAPT (0.51) | HPGDKMT2AMEN1MAPTMAPK1 | |
| SCHEMBL14207854 | 0.67 | HPGD (0.47) | HPGDKMT2AMEN1MAPTMAPK1 | |
| SCHEMBL24538828 | 0.66 | PARP10 (0.70) | HPGDKMT2AMEN1MAPTMAPK1 | |
| SCHEMBL10494485 | 0.66 | PARP10 (0.70) | HPGDKMT2AMEN1MAPTMAPK1 | |
| SCHEMBL21246920 | 0.66 | RXFP1 (0.70) | HPGDKMT2AMEN1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011155983-A1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS INC. (US) | 2011-12-15 | — | — | WO | disclosed |