Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.70 |
| ▸ | RAB9A | P51151 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | CES2 | O00748 | 2/20 | 0.64 |
| ▸ | CES1 | P23141 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 5/20 | 0.61 |
| ▸ | CA2 | P00918 | 5/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.61 |
| ▸ | TUBB | P07437 | 1/20 | 0.61 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.61 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9418310 | 0.93 | RXFP1 (0.79) | RXFP1RAB9AMEN1LMNAMAPT | |
| SCHEMBL51509 | 0.93 | RXFP1 (0.79) | RXFP1RAB9AMEN1LMNAMAPT | |
| SCHEMBL18545953 | 0.92 | CES2 (0.69) | RXFP1RAB9AMEN1LMNAMAPT | |
| SCHEMBL12341716 | 0.92 | LMNA (0.61) | RXFP1RAB9AMEN1LMNAMAPT | |
| SCHEMBL10093719 | 0.92 | LMNA (0.61) | RXFP1RAB9AMEN1LMNAMAPT | |
| SCHEMBL2998614 | 0.92 | CES2 (0.69) | RXFP1RAB9AMEN1LMNAMAPT | |
| SCHEMBL21679502 | 0.90 | RAB9A (0.89) | RXFP1RAB9AMEN1LMNAMAPT | |
| Ethyne SCHEMBL8195983 | 0.88 | RXFP1 (0.73) | RXFP1RAB9AMEN1LMNAMAPT | |
| Anisole SCHEMBL27657177 | 0.88 | CES2 (0.58) | RXFP1RAB9AMEN1LMNAMAPT | |
| SCHEMBL24489353 | 0.87 | CES2 (0.62) | RXFP1RAB9AMEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110072844-B | Compounds for the treatment of infection by Mannheimia haemolytica or histophilus somni | 英特维特国际股份有限公司 | 2023-06-02 | — | — | CN | disclosed |
| CN-111094557-B | Alcohol dehydrogenase mutant and application thereof in synthesis of diaryl chiral alcohol | 江南大学 | 2022-11-11 | — | — | CN | disclosed |
| CN-111433357-B | Alcohol dehydrogenase mutant and application thereof in synthesis of diaryl chiral alcohol | 江南大学 | 2022-11-11 | — | — | CN | disclosed |
| CN-111433357-A | Alcohol dehydrogenase mutant and application thereof in synthesis of diaryl chiral alcohol | 江南大学 | 2020-07-17 | — | — | CN | disclosed |
| WO-2019153634-A1 | ALCOHOL DEHYDROGENASE MUTANT AND APPLICATION THEREOF IN SYNTHESIS OF BIARYL CHIRAL ALCOHOL | 江南大学 | 2019-08-15 | — | — | WO | disclosed |
| WO-2019153632-A1 | ALCOHOL DEHYDROGENASE MUTANT AND APPLICATION THEREOF IN SYNTHEISIS OF DIARYL CHIRAL ALCOHOL | 江南大学 | 2019-08-15 | — | — | WO | disclosed |
| WO-2019153633-A1 | ALCOHOL DEHYDROGENASE MUTANT AND APPLICATION THEREOF IN SYNTHEISIS OF DIARYL CHIRAL ALCOHOL | 江南大学 | 2019-08-15 | — | — | WO | disclosed |
| CN-1688549-A | Compound having TGF-beta inhibitory activity and medicinal composition containing the same | KIRIN BREWERY (JP) | 2005-10-26 | — | — | CN | disclosed |