Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15284855 | 0.91 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL14252722 | 0.89 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL2641242 | 0.82 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL2489450 | 0.80 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL24178952 | 0.74 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL9259862 | 0.73 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL16303102 | 0.69 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL11272258 | 0.68 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL11839696 | 0.68 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| N,N-Diallyl-2-Chloroacetamide SCHEMBL53540 | 0.68 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107997-B1 | POLYMER PRODUCTION | QINETIQ LTD (GB) | 2010-01-27 | — | — | EP | disclosed |