Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2489450 | 0.78 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL16500488 | 0.73 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL7155920 | 0.69 | CHRNB2 (0.38) | ALDH1A1 | |
| SCHEMBL11442766 | 0.68 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL3360577 | 0.67 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL10645801 | 0.67 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL2641242 | 0.67 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL6827624 | 0.67 | TDP1 (0.40) | ALDH1A1MAPT | |
| SCHEMBL569156 | 0.66 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL13786 | 0.66 | ALDH1A1 (0.56) | ALDH1A1KDM4ESMN1; SMN2MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0476785-B1 | Processes for the preparation of aminoethers | OSI SPECIALTIES INC (US) | 1995-12-06 | — | — | EP | claimed |
| US-5214142-A | PROCESSES FOR THE PREPARATION OF AMINOETHERS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1993-05-25 | — | — | US | claimed |
| EP-0476785-A1 | Processes for the preparation of aminoethers | OSi Specialties, Inc. (US) | 1992-03-25 | — | — | EP | claimed |
| EP-0476785-B1 | Processes for the preparation of aminoethers | OSI SPECIALTIES INC (US) | 1995-12-06 | — | — | EP | disclosed |
| EP-0640388-A1 | Magnesium/aluminum mixed oxide catalysts and their use in the production of aminoethers | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1995-03-01 | — | — | EP | disclosed |
| US-5214142-A | PROCESSES FOR THE PREPARATION OF AMINOETHERS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1993-05-25 | — | — | US | disclosed |
| EP-0476785-A1 | Processes for the preparation of aminoethers | OSi Specialties, Inc. (US) | 1992-03-25 | — | — | EP | disclosed |