Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TSPO | P30536 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17122363 | 0.95 | KDM4E (0.48) | KDM4EATML3MBTL1HDAC4ALDH1A1 | |
| SCHEMBL17122361 | 0.92 | ALDH1A1 (0.33) | KDM4EATML3MBTL1HDAC4ALDH1A1 | |
| SCHEMBL559718 | 0.89 | L3MBTL1 (0.53) | KDM4EATML3MBTL1HDAC4ALDH1A1 | |
| SCHEMBL15158496 | 0.88 | ALDH1A1 (0.40) | KDM4EATML3MBTL1HDAC4ALDH1A1 | |
| SCHEMBL16500780 | 0.88 | KDM4E (0.50) | KDM4EATML3MBTL1HDAC4ALDH1A1 | |
| SCHEMBL16500889 | 0.87 | KDM4E (0.57) | KDM4EATML3MBTL1HDAC4ALDH1A1 | |
| SCHEMBL30516768 | 0.86 | L3MBTL1 (0.48) | KDM4EATML3MBTL1HDAC4ALDH1A1 | |
| SCHEMBL22903440 | 0.86 | L3MBTL1 (0.48) | KDM4EATML3MBTL1HDAC4ALDH1A1 | |
| SCHEMBL14913074 | 0.86 | L3MBTL1 (0.52) | KDM4EATML3MBTL1HDAC4ALDH1A1 | |
| SCHEMBL30040723 | 0.86 | L3MBTL1 (0.52) | KDM4EATML3MBTL1HDAC4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9145363-B2 | Aromatic amine derivative and organic electroluminescent element | IDEMITSU KOSAN CO., LTD. (JP) | 2015-09-29 | — | — | US | disclosed |
| US-9145363-B2 | Aromatic amine derivative and organic electroluminescent element | IDEMITSU KOSAN CO., LTD. (JP) | 2015-09-29 | — | — | US | disclosed |
| US-20110297924-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT | IDEMITSU KOSAN CO., LTD. (JP) | 2011-12-08 | — | — | US | disclosed |
| US-20110297924-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT | IDEMITSU KOSAN CO., LTD. (JP) | 2011-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110297924-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT | SLC18A2, SLC18A1, SLC7A5 | KDM4E 214/4885ATM 1297/4885L3MBTL1 1214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.