SCHEMBL559718

SCHEMBL559718

Ic1ccc2c(c1)c1ccccc1n2-c1ccc(-c2ccccc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.53
KDM4E B2RXH2 2/20 0.53
ATM Q13315 1/20 0.53
HDAC4 P56524 1/20 0.43
KMT2A Q03164 3/20 0.38
IL1R1 P14778 1/20 0.38
TSPO P30536 1/20 0.37
MEN1 O00255 2/20 0.37
MAPT P10636 2/20 0.37
ALDH1A1 P00352 1/20 0.37
HTT P42858 1/20 0.37
RAC2 P15153 1/20 0.36
RAC3 P60763 1/20 0.36
CDC42 P60953 1/20 0.36
RAC1 P63000 1/20 0.36
PTPN1 P18031 2/20 0.35
EDNRA P25101 2/20 0.35
EDNRB P24530 1/20 0.35
DNMT1 P26358 1/20 0.35
AKR1C4 P17516 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24736252 0.92 L3MBTL1 (0.52) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL16500889 0.92 KDM4E (0.57) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL17658828 0.90 L3MBTL1 (0.58) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL27883966 0.90 L3MBTL1 (0.67) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL296550 0.90 L3MBTL1 (0.67) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL16501005 0.89 KDM4E (0.44) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL19695645 0.89 KDM4E (0.47) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL3332174 0.89 L3MBTL1 (0.60) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL3382322 0.89 L3MBTL1 (0.46) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL16693495 0.88 ATM (0.50) L3MBTL1KDM4EATMHDAC4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2085382-B1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO (JP) 2016-04-20 EP disclosed
US-8895159-B2 Aromatic amine derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-11-25 US disclosed
US-8895159-B2 Aromatic amine derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-11-25 US disclosed
US-20130187137-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-07-25 US disclosed
US-20130187137-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-07-25 US disclosed
US-8405070-B2 Composite material, and light emitting element and light emitting device using the composite material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-03-26 US disclosed
US-8405070-B2 Composite material, and light emitting element and light emitting device using the composite material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-03-26 US disclosed
US-8405070-B2 Composite material, and light emitting element and light emitting device using the composite material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-03-26 US disclosed
US-8394510-B2 Aromatic amine derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2013-03-12 US disclosed
US-8394510-B2 Aromatic amine derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2013-03-12 US disclosed
US-20080099757-A1 Organic field effect transistor and semiconductor device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-05-01 US disclosed
US-20080099757-A1 Organic field effect transistor and semiconductor device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-05-01 US disclosed
US-20080099757-A1 Organic field effect transistor and semiconductor device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-05-01 US disclosed
EP-1910289-A1 CARBAZOLE DERIVATIVE, LIGHT-EMITTING ELEMENT MATERIAL OBTAINED BY USING CARBAZOLE DERIVATIVE, LIGHT-EMITTING ELEMENT, AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-04-16 EP disclosed
WO-2007086534-A1 ORGANIC FIELD EFFECT TRANSISTOR AND SEMICONDUCTOR DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-08-02 WO disclosed
US-20070031701-A1 Carbazole derivative, light-emitting element material obtained by using carbazole derivative, light-emitting element, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-02-08 US disclosed
US-20070031701-A1 Carbazole derivative, light-emitting element material obtained by using carbazole derivative, light-emitting element, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-02-08 US disclosed
US-20070031701-A1 Carbazole derivative, light-emitting element material obtained by using carbazole derivative, light-emitting element, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-02-08 US disclosed
WO-2007015407-A1 CARBAZOLE DERIVATIVE, LIGHT-EMITTING ELEMENT MATERIAL OBTAINED BY USING CARBAZOLE DERIVATIVE, LIGHT-EMITTING ELEMENT, AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-02-08 WO disclosed
WO-2006070912-A1 CARBAZOLE DERIVATIVE, AND LIGHT-EMITTING ELEMENT AND LIGHT-EMITTING DEVICE USING THE CARBAZOLE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2006-07-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070031701-A1 Carbazole derivative, light-emitting element material obtained by using carbazole derivative, light-emitting element, and electronic device CYP1A1, GRIA1, GNA11 L3MBTL1 221/4885KDM4E 2231/4885ATM 1256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.