Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16501933 | 0.91 | SHMT1 (0.36) | TRPM8PTGDR2CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL1922453 | 0.89 | PTGDR2 (0.50) | PTGDR2TBXA2RPTGDR | |
| SCHEMBL16501867 | 0.88 | PTGDR2 (0.43) | TRPM8PTGDR2CYP11B1CYP11B2LMNA | |
| SCHEMBL16501944 | 0.84 | ALDH1A1 (0.46) | TRPM8PTGDR2CYP11B1CYP11B2LMNA | |
| SCHEMBL16501935 | 0.84 | CYP11B1 (0.42) | TRPM8PTGDR2CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL16501913 | 0.83 | LMNA (0.46) | TRPM8PTGDR2CYP11B1CYP11B2LMNA | |
| SCHEMBL16501939 | 0.83 | TRPM8 (0.46) | TRPM8LMNATP53ALDH1A1POLB | |
| SCHEMBL16501932 | 0.83 | TRPM8 (0.45) | TRPM8PTGDR2CYP11B1CYP11B2LMNA | |
| SCHEMBL16501926 | 0.82 | CYP11B1 (0.39) | TRPM8PTGDR2CYP11B1CYP11B2LMNA | |
| SCHEMBL16501924 | 0.81 | TRPM8 (0.36) | TRPM8ALDH1A1NPC1NFKB1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110312974-A1 | HETEROARYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2011-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110312974-A1 | HETEROARYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | PTGDR, PTGDR2, PTGER2 | TRPM8 743/4885PTGDR2 2/4885CYP11B1 173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.