Ornipressin

Ornipressin

SCHEMBL5200435

NCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)NCC(N)=O.O=C(O)C(F)(F)F

nearest known ligand 0.83

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ AVPR1A P37288 10/20 0.83
▸ AVPR1B P47901 8/20 0.83
▸ AVPR2 P30518 7/20 0.83
▸ OXTR P30559 7/20 0.83
▸ TBXA2R P21731 1/20 0.75
▸ PDE4D Q08499 1/20 0.75
▸ PDE3A Q14432 1/20 0.75
▸ PTGS1 P23219 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ornipressin SCHEMBL1650220 0.97 AVPR1A (0.88) AVPR1AAVPR1BAVPR2OXTRTBXA2R
Ornipressin SCHEMBL296322 0.97 AVPR1A (0.88) AVPR1AAVPR1BAVPR2OXTRTBXA2R
Felypressin SCHEMBL5199973 0.96 AVPR1A (0.77) AVPR1AAVPR1BAVPR2OXTRTBXA2R
Ornipressin SCHEMBL4410141 0.95 AVPR1A (0.85) AVPR1AAVPR1BAVPR2OXTRTBXA2R
Lypressin SCHEMBL1650587 0.95 OXTR (0.87) AVPR1AAVPR1BAVPR2OXTRTBXA2R
Lypressin SCHEMBL33287 0.95 OXTR (0.87) AVPR1AAVPR1BAVPR2OXTRTBXA2R
Lypressin SCHEMBL29471105 0.94 OXTR (0.84) AVPR1AAVPR1BAVPR2OXTRTBXA2R
SCHEMBL24239052 0.93 OXTR (0.82) AVPR1AAVPR1BAVPR2OXTRTBXA2R
Felypressin SCHEMBL1650172 0.92 AVPR1A (0.82) AVPR1AAVPR1BAVPR2OXTRTBXA2R
Felypressin SCHEMBL31138866 0.92 AVPR1A (0.82) AVPR1AAVPR1BAVPR2OXTRTBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1773870-A2 METHODS FOR THE PRODUCTION OF PEPTIDE HAVING A C-TERMINAL AMIDE Novetide Ltd. (IL) 2007-04-18 — — EP disclosed
US-20060276626-A1 Methods for the production of peptide derivatives TEVA PHARMACEUTICALS USA, INC. 2006-12-07 — — US disclosed
WO-2006119388-A2 METHODS FOR THE PRODUCTION OF PEPTIDE HAVING A C-TERMINAL AMIDE NOVETIDE, LTD. (IL) 2006-11-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060276626-A1 Methods for the production of peptide derivatives VIP, IAPP, PTMS AVPR1A 349/4885AVPR1B 376/4885AVPR2 177/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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