Pinosylvin Methyl Ether

Pinosylvin Methyl Ether

SCHEMBL1650248

COc1cc(O)cc(C=Cc2ccccc2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 1.00
MEN1 O00255 2/20 1.00
MAPT P10636 2/20 1.00
KMT2A Q03164 2/20 1.00
USP2 O75604 1/20 1.00
ALDH1A1 P00352 1/20 1.00
TP53 P04637 1/20 1.00
CYP3A4 P08684 1/20 1.00
HPGD P15428 1/20 1.00
SMN1; SMN2 Q16637 1/20 1.00
TRPV1 Q8NER1 1/20 1.00
HSD17B10 Q99714 1/20 1.00
CYP1A1 P04798 7/20 0.77
CYP1B1 Q16678 6/20 0.77
PTGS2 P35354 4/20 0.77
TTR P02766 3/20 0.77
ALOX5 P09917 3/20 0.77
ABL1 P00519 4/20 0.69
BCR P11274 4/20 0.69
ABCB1 P08183 3/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pinosylvin Methyl Ether SCHEMBL9419826 1.00 KDM4E (1.00) KDM4EMEN1MAPTKMT2AUSP2
Pinosylvin Methyl Ether SCHEMBL29928865 1.00 KDM4E (1.00) KDM4EMEN1MAPTKMT2AUSP2
Pinosylvin Methyl Ether SCHEMBL1650247 1.00 KDM4E (1.00) KDM4EMEN1MAPTKMT2AUSP2
Pinosylvin Methyl Ether SCHEMBL30334927 1.00 KDM4E (1.00) KDM4EMEN1MAPTKMT2AUSP2
Pterostilbene SCHEMBL3476943 0.89 NQO2 (0.86) KDM4EMEN1MAPTKMT2AUSP2
Pterostilbene SCHEMBL3476941 0.89 NQO2 (0.86) KDM4EMEN1MAPTKMT2AUSP2
3,5-O-Dimethylpinosylvin SCHEMBL918726 0.88 KDM4E (0.79) KDM4EMEN1MAPTKMT2AUSP2
3,5-O-Dimethylpinosylvin SCHEMBL9419809 0.88 KDM4E (0.79) KDM4EMEN1MAPTKMT2AUSP2
3,5-O-Dimethylpinosylvin SCHEMBL918727 0.88 KDM4E (0.79) KDM4EMEN1MAPTKMT2AUSP2
SCHEMBL23410069 0.87 ABL1 (0.90) KDM4EMEN1MAPTKMT2AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4436538-A1 COSMETIC OR PHARMACEUTICAL PREPARATION FOR SKIN CARE AND IMPROVING SKIN CONDITION Merryvital AG (CH) 2024-10-02 EP claimed
CN-118401224-A Cosmetic or cosmeceutical product for skin care and improving skin condition 迈瑞维拓股份公司 2024-07-26 CN claimed
WO-2023094852-A1 COSMETIC OR PHARMACEUTICAL PREPARATION FOR SKIN CARE AND IMPROVING SKIN CONDITION MERRYVITAL AG (CH) 2023-06-01 WO claimed
WO-2009118338-A2 USE OF A POLYPHENOLIC TYPE COMPOUND FOR PREVENTING OR TREATING A POLYGLUTAMINE EXPANSION NEURODEGENERATIVE DISEASE INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2009-10-01 WO claimed
EP-2005941-A2 Cellular rejuvenation compounds Henkel AG & Co. KGaA (DE) 2008-12-24 EP claimed
US-20080139650-A1 Fungicidally Active Polymer Dispersions And Use Thereof CELANESE EMULSIONS GMBH (DE) 2008-06-12 US claimed
US-20070292545-A1 ANTI-INFECTIVE AGENTS AND METHODS OF USE WISYS TECHNOLOGY FOUNDATION 2007-12-20 US claimed
JP-9241617-A None JP disclosed
EP-4436538-A1 COSMETIC OR PHARMACEUTICAL PREPARATION FOR SKIN CARE AND IMPROVING SKIN CONDITION Merryvital AG (CH) 2024-10-02 EP disclosed
CN-118401224-A Cosmetic or cosmeceutical product for skin care and improving skin condition 迈瑞维拓股份公司 2024-07-26 CN disclosed
WO-2023094852-A1 COSMETIC OR PHARMACEUTICAL PREPARATION FOR SKIN CARE AND IMPROVING SKIN CONDITION MERRYVITAL AG (CH) 2023-06-01 WO disclosed
CN-113244203-A 9, 10-dihydrophenanthrenes and their use for the treatment of liver injury 中国科学院上海药物研究所 2021-08-13 CN disclosed
EP-2238967-B1 Skin treatment fighting skin aging II HENKEL AG & CO KGAA (DE) 2018-05-02 EP disclosed
US-20020055541-A1 Compositions containing hypotriglyceridemically active stilbenoids SHAMAN PHARMACEUTICALS, INC. 2002-05-09 US disclosed
WO-2002013811-A2 COMPOSITIONS CONTAINING HYPOGLYCEMICALLY ACTIVE STILBENOIDS INSMED INCORPORATED (US) 2002-02-21 WO disclosed
WO-2002013809-A2 COMPOSITIONS CONTAINING HYPOTRIGLYCERIDEMICALLY ACTIVE STILBENOIDS INSMED INCORPORATED (US) 2002-02-21 WO disclosed
WO-2002014252-A2 COMPOSITIONS CONTAINING HYPOGLYCEMICALLY ACTIVE STILBENOIDS INSMED INCORPORATED (US) 2002-02-21 WO disclosed
WO-2002013806-A2 COMPOSITIONS CONTAINING HYPOTRIGLYCERIDEMICALLY ACTIVE STILBENOIDS INSMED INCORPORATED (US) 2002-02-21 WO disclosed
JP-H09241617-A ULTRAVIOLET ABSORBENT YUSHIRO CHEM IND CO LTD 1997-09-16 JP disclosed
US-5314693-A Hydroxystilbene compounds KIORITZ CORPORATION (JP) 1994-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080139650-A1 Fungicidally Active Polymer Dispersions And Use Thereof CBR3, CBR1, CYP3A4 KDM4E 1199/4885MEN1 2062/4885MAPT 3690/4885
US-20020055541-A1 Compositions containing hypotriglyceridemically active stilbenoids CPT1B, CPT1A, LIPC KDM4E 3393/4885MEN1 2300/4885MAPT 1859/4885
US-20070292545-A1 ANTI-INFECTIVE AGENTS AND METHODS OF USE H1-3, H1-0, H1-2 KDM4E 1612/4885MEN1 2664/4885MAPT 4879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.