Pinosylvin Methyl Ether

Pinosylvin Methyl Ether

SCHEMBL1650247

COc1cc(O)cc(/C=C/c2ccccc2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 1.00
MEN1 O00255 2/20 1.00
MAPT P10636 2/20 1.00
KMT2A Q03164 2/20 1.00
USP2 O75604 1/20 1.00
ALDH1A1 P00352 1/20 1.00
TP53 P04637 1/20 1.00
CYP3A4 P08684 1/20 1.00
HPGD P15428 1/20 1.00
SMN1; SMN2 Q16637 1/20 1.00
TRPV1 Q8NER1 1/20 1.00
HSD17B10 Q99714 1/20 1.00
CYP1A1 P04798 7/20 0.77
CYP1B1 Q16678 6/20 0.77
PTGS2 P35354 4/20 0.77
TTR P02766 3/20 0.77
ALOX5 P09917 3/20 0.77
ABL1 P00519 4/20 0.69
BCR P11274 4/20 0.69
ABCB1 P08183 3/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pinosylvin Methyl Ether SCHEMBL9419826 1.00 KDM4E (1.00) KDM4EMEN1MAPTKMT2AUSP2
Pinosylvin Methyl Ether SCHEMBL29928865 1.00 KDM4E (1.00) KDM4EMEN1MAPTKMT2AUSP2
Pinosylvin Methyl Ether SCHEMBL1650248 1.00 KDM4E (1.00) KDM4EMEN1MAPTKMT2AUSP2
Pinosylvin Methyl Ether SCHEMBL30334927 1.00 KDM4E (1.00) KDM4EMEN1MAPTKMT2AUSP2
Pterostilbene SCHEMBL3476943 0.89 NQO2 (0.86) KDM4EMEN1MAPTKMT2AUSP2
Pterostilbene SCHEMBL3476941 0.89 NQO2 (0.86) KDM4EMEN1MAPTKMT2AUSP2
3,5-O-Dimethylpinosylvin SCHEMBL918726 0.88 KDM4E (0.79) KDM4EMEN1MAPTKMT2AUSP2
3,5-O-Dimethylpinosylvin SCHEMBL9419809 0.88 KDM4E (0.79) KDM4EMEN1MAPTKMT2AUSP2
3,5-O-Dimethylpinosylvin SCHEMBL918727 0.88 KDM4E (0.79) KDM4EMEN1MAPTKMT2AUSP2
SCHEMBL23410069 0.87 ABL1 (0.90) KDM4EMEN1MAPTKMT2AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115541792-B Quality control method and application of Chinese pine knot formula particles 北京康仁堂药业有限公司 2024-12-20 CN claimed
EP-4436538-A1 COSMETIC OR PHARMACEUTICAL PREPARATION FOR SKIN CARE AND IMPROVING SKIN CONDITION Merryvital AG (CH) 2024-10-02 EP claimed
CN-118401224-A Cosmetic or cosmeceutical product for skin care and improving skin condition 迈瑞维拓股份公司 2024-07-26 CN claimed
CN-113842390-B Lindera fruticosa active ingredient composition with gastric ulcer prevention and treatment effect, and preparation method and application thereof 河南中医药大学 2024-03-12 CN claimed
WO-2023094852-A1 COSMETIC OR PHARMACEUTICAL PREPARATION FOR SKIN CARE AND IMPROVING SKIN CONDITION MERRYVITAL AG (CH) 2023-06-01 WO claimed
US-20230012268-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF INFLAMMATION WITH STEROIDS AND A MODULATOR BUZZELET DEVELOPMENT AND TECHNOLOGIES LTD (IL) 2023-01-12 US claimed
CN-115541792-A Quality control method of Chinese pine knot formula granules and application thereof 北京康仁堂药业有限公司 2022-12-30 CN claimed
EP-4072558-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF INFLAMMATION WITH STEROIDS AND A MODULATOR Buzzelet Development And Technologies Ltd (IL) 2022-10-19 EP claimed
US-20220233463-A1 LOCAL ANESTHETIC COMPRISING A TRP CHANNEL MODULATOR BUZZELET DEVELOPMENT AND TECHNOLOGIES LTD (IL) 2022-07-28 US claimed
EP-4017486-A1 COMPOSITONS FOR THE TREATMENT OF A CONDITION CHARACTERIZED BY ANANDAMIDE DEFICIENCY AND USES THEREOF Buzzelet Development And Technologies Ltd (IL) 2022-06-29 EP claimed
WO-2021033149-A1 COMPOSITONS FOR THE TREATMENT OF A CONDITION CHARACTERIZED BY ANANDAMIDE DEFICIENCY AND USES THEREOF BUZZELET DEVELOPMENT AND TECHNOLOGIES LTD. (IL) 2021-02-25 WO claimed
WO-2020230071-A1 LOCAL ANESTHETIC COMPRISING A TRP CHANNEL MODULATOR BUZZELET DEVELOPMENT AND TECHNOLOGIES LTD. (IL) 2020-11-19 WO claimed
US-20130245070-A1 COMPOUNDS FOR ENHANCING ARGINASE ACTIVITY AND METHODS OF USING SAME THE RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) 2013-09-19 US claimed
US-20090253782-A1 Compounds for Enhancing Arginase Activity and Methods of USe Thereof CORNELL RESEARCH FOUNDATION, INC. 2009-10-08 US claimed
WO-2009118338-A2 USE OF A POLYPHENOLIC TYPE COMPOUND FOR PREVENTING OR TREATING A POLYGLUTAMINE EXPANSION NEURODEGENERATIVE DISEASE INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2009-10-01 WO claimed
EP-2005941-A2 Cellular rejuvenation compounds Henkel AG & Co. KGaA (DE) 2008-12-24 EP claimed
US-20080139650-A1 Fungicidally Active Polymer Dispersions And Use Thereof CELANESE EMULSIONS GMBH (DE) 2008-06-12 US claimed
WO-2008011083-A2 COMPOUNDS FOR ENHANCING ARGINASE ACTIVITY AND METHODS OF USE THEREOF CORNELL RESEARCH FOUNDATION, INC. (US) 2008-01-24 WO claimed
US-20070292545-A1 ANTI-INFECTIVE AGENTS AND METHODS OF USE WISYS TECHNOLOGY FOUNDATION 2007-12-20 US claimed
CN-1553887-A Method for separating phenolic substances or juvabiones from wood containing nodular wood �����ᡤ����ķ��ķ 2004-12-08 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080139650-A1 Fungicidally Active Polymer Dispersions And Use Thereof CBR3, CBR1, CYP3A4 KDM4E 1199/4885MEN1 2062/4885MAPT 3690/4885
US-20130245070-A1 COMPOUNDS FOR ENHANCING ARGINASE ACTIVITY AND METHODS OF USING SAME ARG2, ARG1, OTC KDM4E 1426/4885MEN1 3845/4885MAPT 3632/4885
US-20070292545-A1 ANTI-INFECTIVE AGENTS AND METHODS OF USE H1-3, H1-0, H1-2 KDM4E 1612/4885MEN1 2664/4885MAPT 4879/4885
US-20090253782-A1 Compounds for Enhancing Arginase Activity and Methods of USe Thereof ARG2, ARG1, OTC KDM4E 1521/4885MEN1 3962/4885MAPT 3726/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.