Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 3/20 | 0.90 |
| ▸ | BCR | P11274 | 3/20 | 0.90 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.77 |
| ▸ | MAPT | P10636 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | USP2 | O75604 | 1/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.77 |
| ▸ | TP53 | P04637 | 1/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.77 |
| ▸ | HPGD | P15428 | 1/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.77 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.77 |
| ▸ | LCK | P06239 | 1/20 | 0.69 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.69 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.69 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.69 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.69 |
| ▸ | TTR | P02766 | 2/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15247611 | 1.00 | ABL1 (0.90) | ABL1BCRKDM4EMEN1MAPT | |
| SCHEMBL29860087 | 1.00 | ABL1 (0.90) | ABL1BCRKDM4EMEN1MAPT | |
| SCHEMBL22245457 | 1.00 | ABL1 (0.90) | ABL1BCRKDM4EMEN1MAPT | |
| SCHEMBL23754583 | 0.95 | ABL1 (1.00) | ABL1BCRKDM4EMEN1MAPT | |
| SCHEMBL23754271 | 0.95 | ABL1 (1.00) | ABL1BCRKDM4EMEN1MAPT | |
| SCHEMBL23754584 | 0.95 | ABL1 (1.00) | ABL1BCRKDM4EMEN1MAPT | |
| SCHEMBL23754270 | 0.95 | ABL1 (1.00) | ABL1BCRKDM4EMEN1MAPT | |
| SCHEMBL30176051 | 0.93 | KDM4E (0.77) | ABL1BCRKDM4EMEN1MAPT | |
| SCHEMBL9419831 | 0.89 | ABL1 (0.83) | ABL1BCRKDM4EMEN1MAPT | |
| SCHEMBL9419833 | 0.89 | ABL1 (0.83) | ABL1BCRKDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230008317-A1 | Z-STILBENE AMPK ACTIVATOR COMPOUNDS, COMPOSITIONS, METHODS AND USES THEREOF | NESTLE SA (CH) | 2023-01-12 | — | — | US | claimed |
| CN-114650812-A | Z-stilbene AMPK activator compounds, compositions, methods, and uses thereof | 雀巢产品有限公司 | 2022-06-21 | — | — | CN | claimed |
| WO-2021105076-A1 | Z-STILBENE AMPK ACTIVATOR COMPOUNDS, COMPOSITIONS, METHODS AND USES THEREOF | Société des Produits Nestlé S.A. (CH) | 2021-06-03 | — | — | WO | claimed |
| US-20230008317-A1 | Z-STILBENE AMPK ACTIVATOR COMPOUNDS, COMPOSITIONS, METHODS AND USES THEREOF | NESTLE SA (CH) | 2023-01-12 | — | — | US | disclosed |
| US-20230008317-A1 | Z-STILBENE AMPK ACTIVATOR COMPOUNDS, COMPOSITIONS, METHODS AND USES THEREOF | NESTLE SA (CH) | 2023-01-12 | — | — | US | disclosed |
| CN-114650812-A | Z-stilbene AMPK activator compounds, compositions, methods, and uses thereof | 雀巢产品有限公司 | 2022-06-21 | — | — | CN | disclosed |
| WO-2021105076-A1 | Z-STILBENE AMPK ACTIVATOR COMPOUNDS, COMPOSITIONS, METHODS AND USES THEREOF | Société des Produits Nestlé S.A. (CH) | 2021-06-03 | — | — | WO | disclosed |
| WO-2021105076-A1 | Z-STILBENE AMPK ACTIVATOR COMPOUNDS, COMPOSITIONS, METHODS AND USES THEREOF | Société des Produits Nestlé S.A. (CH) | 2021-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230008317-A1 | Z-STILBENE AMPK ACTIVATOR COMPOUNDS, COMPOSITIONS, METHODS AND USES THEREOF | PRKAG1, PRKAB1, PRKAB2 | ABL1 1671/4885BCR 3517/4885KDM4E 1620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.